Introduction Autoinflammatory disorders are a group of diseases whose nosology and etiology are only partly understood. Among Mendelian forms, familial Mediterranean fever (FMF), due to mutations in MEFV, is one of the most frequent. Most MEFV mutations are located in exon 10 and are usually associated with an autosomal recessive mode of inheritance. MEFV encodes pyrin, which interacts with PST...

University of Konstanz and for coaching me through the project. Thanks to the Haematox group for the scientific but also personal support: you are not only colleagues but really good friends! Thanks to Dr. Michele Reni for the constant presence, for the optimism and for making endurable the therapy. Finally, this work is dedicated to the most important people in my life: mamma, papa' and Tommaso.

O1 Ticks feeding on ruminants and humans in Greece I Chaligiannis, A Papa, S Sotiraki State Veterinary Laboratory of Thrace, Ministry of Rural Development and Food, Komotini 691 00, Greece; Veterinary Research Institute of Thessaloniki, HAO-Demeter (former NAGREF), Thermi 57001, Thessaloniki, Greece; A’ Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloni...

Romina Papa Ezdra, Inés Bado, Nicolás Cordeiro, Claudia Gutierrez, Patricia Hitateguy, Verónica Seija, Rafael Vignoli Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay; Departamento de Laboratorio Clínico, Área Microbiología, Hospital de Clínicas, Facultad de Medicina, Universidad de la República, Montevideo, ...

This paper outlines the possibilities, the evolution, and the basic technical elements of autonomously hovering micro robots. It consists of three parts. The first part presents the application Papa-TV-Bot, a free flying automatic video camera. The second part is a schedule for the long-term development of autonomously hovering mobots in 8 phases. The third part describes the basic technologies...

Federica Casiraghi, Monica Cortinovis, Norberto Perico, and Giuseppe Remuzzi IRCCS-Istituto di Ricerche Farmacologiche “Mario Negri,” Transplant Research Center “Chiara Cucchi de Alessandri e Gilberto Crespi,” Ranica, Bergamo, Italy; IRCCS-Istituto di Ricerche Farmacologiche “Mario Negri,” Clinical Research Center for Rare Diseases “Aldo e Cele Daccò,” Ranica, Bergamo, Italy; Unit of Nephrology...

1Neurology Service of Hospital das Nações, Curitiba PR, Brazil; 2Movement Disorders Unit, Neurology Service, Federal University of Paraná (UFPR), Curitiba PR, Brazil. Correspondence: Giorgio Fabiani; Rua Raphael Papa 10; 82530-190 Curitiba PR Brasil; E-mail: [email protected] / [email protected] Conflict of interest: There is no conflict of interest to declare. Received 19 Dece...

Vincenza Bagetta,1* Carmelo Sgobio,1* Valentina Pendolino,1 Giulia Del Papa,1 Alessandro Tozzi,1,2 Veronica Ghiglieri,1 Carmela Giampà,1 Elisa Zianni,3 Fabrizio Gardoni,3 Paolo Calabresi,1,2 and Barbara Picconi1 1Laboratorio di Neurofisiologia, Fondazione Santa Lucia, Istituto di Ricovero e Cura a Carattere Scientifico, 00143 Rome, Italy, 2Clinica Neurologica, Università degli Studi di Perugia,...

Introduction Pyogenic sterile Arthritis Pyoderma gangrenosum and Acne (PAPA) syndrome is a rare autosomal dominant inherited autoinflammatory disease caused by mutations in Proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1). In childhood, the syndrome is featured by recurrent sterile, erosive arthritis, potentially leading to joint destruction. By puberty, cutaneous symptoms b...

This paper introduces PAPA: Packed Arithmetic on a Prefix Adder, a new approach to parallel prefix adder design that supports a wide variety of packed arithmetic computations, including packed add and subtract with saturation, packed rounded average, and packed absolute difference. The approach consists of altering the prefix adder cell logic equations to take advantage of a previously unused “...