The sexual Fus3 MAP kinase module of yeast is highly conserved in eukaryotes and transmits external signals from the plasma membrane to the nucleus. We show here that the module of the filamentous fungus Aspergillus nidulans (An) consists of the AnFus3 MAP kinase, the upstream kinases AnSte7 and AnSte11, and the AnSte50 adaptor. The fungal MAPK module controls the coordination of fungal develop...

In this work, a computational study of a series of N-substitued-4-piperidones curcumin analogues is presented. The molecular structure of the neutral molecules and their radical anions, as well as their reactivity, are investigated. N-substituents include methyl and benzyl groups, while substituents on the aromatic rings cover electron-donor and electron-acceptor groups. Substitutions at the ni...

Filamentous fungi produce a number of small bioactive molecules as part of their secondary metabolism ranging from benign antibiotics such as penicillin to threatening mycotoxins such as aflatoxin. Secondary metabolism can be linked to fungal developmental programs in response to various abiotic or biotic external triggers. The velvet family of regulatory proteins plays a key role in coordinati...

The velvet protein, VeA, is involved in the regulation of diverse cellular processes. In this study, we explored functions of FgVeA in the wheat head blight pathogen, Fusarium graminearum,using a gene replacement strategy. The FgVEA deletion mutant exhibited a reduction in aerial hyphae formation, hydrophobicity, and deoxynivalenol (DON) biosynthesis. Deletion of FgVEA gene led to an increase i...

This paper describes the design and development of a sensor based navigation system which makes it possible for a non-holonomous mobile robot to follow walls using information on its environment picked up by a belt of ultrasonic sensors. To control the robot no preliminary information regarding its environment is required, the robot adapts to them through the information gathered on the spot by...

In West Africa, the most extreme predicted effects of climate change are expected to occur in desert and grassland areas. It is crucial for local populations in this region to better understand what such projections signify to them to identify sound adaptation policies and interventions. We developed a game, called the “grazing game,” and conducted trials with local farmers at multiple study si...

Sexual development is regulated by a complex regulatory mechanism in fungi. For Trichoderma reesei, the light response pathway was shown to impact sexual development, particularly through the photoreceptor ENVOY. Moreover, T. reesei communicates chemically with a potential mating partner in its vicinity, a response which is mediated by the velvet family protein VEL1 and its impact on secondary ...

Fungal development and secondary metabolism is intimately associated via activities of the fungi-specific velvet family proteins including VeA, VosA, VelB and VelC. Among these, VelC has not been characterized in Aspergillus nidulans. In this study, we characterize the role of VelC in asexual and sexual development in A. nidulans. The velC mRNA specifically accumulates during the early phase of...

In this paper, a Junctionless Accumulation Mode Ferroelectric Field Effect Transistor (JAM-FE-FET) has been proposed and assessed in terms of RF/analog specifications for varied channel lengths through simulations using TCAD Silvaco ATLAS simulator, the Shockley-Read-Hall (SRH) recombination, ferro, Lombardi CVT, fermi LK models. Major analog metrics like transconductance (gm), intrinsic gain (...