PURPOSE To compare the anterior lens capsulotomy edge tear strength created by manual continuous curvilinear capsulorhexis (CCC), femtosecond laser capsulotomy (FSLC), and a new automated precision pulse capsulotomy (PPC) device. DESIGN A 3-arm study in paired human cadaver eyes. PARTICIPANTS A total of 44 eye specimens from 22 donors in the United States. METHODS Capsulotomy was performe...

BACKGROUND Compassion and collaborative practice are individually associated with high quality healthcare. When combined in a compassionate collaborative care (CCC) practice framework, they are reported to improve health, strengthen care provision, and control health costs. Little is known about how to integrate and measure CCC, yet it is fundamentally applied in palliative and end-of-life care...

Several clinical trials to establish standard treatment modality for ovarian cancers included a high abundance of patients with serous histologic tumors, which were quite sensitive to platinum-based chemotherapy. On the other hand, ovarian tumor with rare histologic subtypes such as clear cell or mucinous tumors have been recognized to show chemo-resistant phenotype, leading to poorer prognosis...

Two concepts for the transmission with a high power capacity using HVDC technology are analysed in this paper. The technology of Capacitor Commutated Converters (CCC) is presented and the design of two system models is described. Their steady-state as well as transient performance is presented and the CCC is compared to the conventional HVDC transmission. The advantages of the CCC for high powe...

it is suggested that cultivars of wheat (triticum aestivum l.) with regulated growth and development would be able to produce higher yields under water-limited conditions, which is crucial in future food production. water use efficiency (wue) is worthy of exploration in this regard. in this study, the effects of nitrogen fertilizer levels (0, 40 and 80 kg nha-1) and a plant growth retardant (ch...

INTRODUCTION Educational milestones are now used to assess the developmental progress of all U.S. graduate medical residents during training. Twice annually, each program's Clinical Competency Committee (CCC) makes these determinations and reports its findings to the Accreditation Council for Graduate Medical Education (ACGME). The ideal way to conduct the CCC is not known. After finding that d...

OBJECTIVE Identifying agreement between data for estimating maximum oxygen uptake obtained by a fitness test and the Polar S810 heart rate monitor. METHODS This was an observational agreement study comparing two methods for estimating VO(2max) (simultaneously and independently). Two protocols were applied to 46 athletes from the Universidad Nacional de Colombia who had been trained in enduran...

AIMS Chagas disease, caused by the protozoan Trypanosoma cruzi is endemic in Latin America, and may lead to a life-threatening inflammatory dilated, chronic Chagas cardiomyopathy (CCC). One third of T. cruzi-infected individuals progress to CCC while the others remain asymptomatic (ASY). A possible genetic component to disease progression was suggested by familial aggregation of cases and the a...

OBJECTIVE The objective of this study was to evaluate the antitumor effects of lurbinectedin as a single agent or in combination with existing anticancer agents for clear cell carcinoma (CCC) of the ovary, which is regarded as an aggressive, chemoresistant, histological subtype. METHODS Using human ovarian CCC cell lines, the antitumor effects of lurbinectedin, SN-38, doxorubicin, cisplatin, ...

BACKGROUND Trypanosoma cruzi ribosomal P proteins, P2β and P0, induce high levels of antibodies in patients with chronic Chagas' disease Cardiomyopathy (CCC). It is well known that these antibodies alter the beating rate of cardiomyocytes and provoke apoptosis by their interaction with β1-adrenergic and M2-muscarinic cardiac receptors. Based on these findings, we decided to study the cellular i...