Objective To explore genetic association between human leukocyte antigen (HLA) and neurodegenerative diseases investigate mechanisms behind the association. Background Pathophysiology of Alzheimer's disease (AD), Parkinson's (PD) amyotrophic lateral sclerosis (ALS) involves accumulation tau (neurofibrillary tangles) amyloid-ß-rich (amyloid plaques) aggregates in AD, a-synuclein-rich (Lewy bodie...

Enterovirus 70 (EV70), an etiological agent of acute hemorrhagic conjunctivitis (AHC), induces apoptosis in human Chang’s conjunctival (HCC) cells. EV70 is also able to infect and replicate in some other human cells such as human lens epithelial SRA01/04 cells and U937 cells. EV70 infection was found to induce apoptosis in SRA01/04 cells. During EV70-induced apoptosis of SRA01/04 cells, the exp...

Fusion products of spleen cells of W/FuDp rats immunized with a methylcholanthrene-induced BALB/c sarcoma, CA-2, and mouse myeloma cells were screened in an attempt to identify a monoclonal antibody defining the individually distinct tumor-specific transplantation antigen of CA-2. A hybridoma, MP/69/04, was isolated which produces an IgG2a monoclonal antibody that recognized a tumor-restricted ...

A Gram-positive, rod-shaped, non-endospore-forming, mycelium-forming actinobacterium (04-St-002(T)) was isolated from the wall of an indoor environment colonized with moulds. On the basis of 16S rRNA gene sequence similarity studies, strain 04-St-002(T) was shown to belong to the family Pseudonocardiaceae, and to be most closely related to Pseudonocardia antarctica (99.2 %) and Pseudonocardia a...

The current pandemic (H1N1) 2009 virus remains transmissible among humans worldwide with cases of reverse zoonosis, providing opportunities to produce more pathogenic variants which could pose greater human health concerns. To investigate whether recent seasonal human or swine H1N1 vaccines could induce cross-reactive immune responses against infection with the pandemic (H1N1) 2009 virus, mice,...

Advanced GeneticsVolume 4, Issue 2 2370022 Editorial BoardOpen Access Board: (Advanced Genetics 2/04) First published: 06 June 2023 https://doi.org/10.1002/ggn2.202370022AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions of Use check box below share version article.I have read accept the Wiley ...

Advanced GeneticsVolume 4, Issue 3 2370032 Editorial BoardOpen Access Board: (Advanced Genetics 3/04) First published: 25 September 2023 https://doi.org/10.1002/ggn2.202370032AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions of Use check box below share version article.I have read accept the W...

Advanced GeneticsVolume 4, Issue 1 2370012 Editorial BoardOpen Access Board: (Advanced Genetics 1/04) First published: 10 March 2023 https://doi.org/10.1002/ggn2.202370012AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions of Use check box below share version article.I have read accept the Wiley...