AIM Neuroprotection trials for neonatal encephalopathy use moderate or severe disability as an outcome, with the Bayley Scales of Infant Development, Second Edition (Bayley-2) Index scores of <70 as part of the criteria. The Bayley Scales of Infant and Toddler, 3rd Development, Third Edition (Bayley-3) have superseded Bayley-2 and yield higher than expected scores in typically developing and hi...

The sampling strategies in many randomized matrix algorithms are, either explicitly or implicitly, controlled by statistical quantities called leverage scores. We present four bounds for the sensitivity of leverage scores as well as an upper bound for the principal angles between two matrices. These bounds are expressed by considering two real m×n matrices of full column rank, A and B. Our boun...

The only approved clot-busting medical treatment in ischemic stroke, intravenous thrombolysis (IVT), is not without complications. One of the major reasons for withholding the therapy remains fear of symptomatic intracranial hemorrhage (sICH), which can worsen patients’ outcomes. The number needed for IVT to cause fatal sICH is 36.5, and to cause any worsening of outcome (≥1 grade on modified R...