HLA-B*13:01 is associated with dapsone (DDS)-induced hypersensitivity and it has been shown that CD4+ CD8+ T cells are activated by DDS its nitroso metabolite (DDS-NO). However, there a need to define the importance of HLA association in disease pathogenesis. Thus, DDS-NO-specific cell clones (TCC) were generated from hypersensitive patients expressing assessed for phenotype function, HLA-allel...

This study is concerned with chronic kidney disease and control group . The determine patients from (alsederhospital ) in Najaf city during the period between January 2019 to July 2019. CKD patient controlgroup consisted of sixty age mean (80 ±20) years. blood samples were drawn all 6hours before after dialysis measurement serotonin , Urea, Creatinine uric acid hemoglobinand group. Also classif...

Local impedance (LI) measurement can predict tissue heating during RF ablation. To evaluate the utility of prespecified target LI to prospectively guide high power, short-duration (HPSD) ablation for PV isolation. This is a single-center prospective study 44 consecutive patients who underwent initial isolation AF. Circumferential around antrum each was performed using 4 mm tip open irrigation c...

Sex-related differences have been reported among patients undergoing pulmonary vein isolation (PVI). Atrial substrate plays a major role in the outcomes after ablation but sex-related atrial never described detail. We sought to analyze remodeling (spontaneous low-voltage zones (LVZ)) and their clinical relevance PVI. conducted prospective multicenter study, including consecutive first PVI-only ...

The World Bank’s health sector projects in Timor-Leste—the Health Sector Rehabilitation and Development Project and the Second Health Sector Rehabilitation and Development Project— have been among the few successful operations it has funded in that country. This paper examines the factors underpinning their relative success and considers the wider lessons of the Bank’s experience for our unders...