An improved understanding of the endocannabinoid system has provided new avenues of drug discovery and development toward the management of pain and other behavioral maladies. Exogenous cannabinoid type 1 (CB1) receptor agonists such as Δ9-tetrahydrocannabinol are increasingly used for their medicinal actions; however, their utility is constrained by concern regarding abuse-related subjective e...

Dendritic cells (DCs) are the most potent APCs of the immune system that seed the peripheral tissues and lymphoid organs. In an immature state, DCs sample their surroundings for incoming pathogens. Upon Ag encounter, DCs mature and migrate to the lymph node to induce adaptive immune responses. The C-type macrophage galactose-type lectin (MGL), expressed in immature DCs, mediates binding to glyc...

Butachlor (N-(butoxymethyl)-2-chloro-N-2, 6-diethylacetanillide) is widely used chloroacetanilide herbicide in Asian region, especially in the north of Iran. Several studies have been reported on toxicity of butachlor, but little information is accessible on DNA damaging potential. Thus, the present study was undertaken to investigate of DNA damage by butachlor in Cyprinuscarpio(Pisces: Cyprini...

BACKGROUND AND PURPOSE The endocannabinoids, N-arachidonoylethanolamide (anandamide) and 2-arachidonoylglycerol (2-AG) are rapidly degraded by fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGL). Whilst these lipid mediators are known to modulate vascular tone, the extent to which they are inactivated via local metabolism in the vasculature remains unclear. EXPERIMENTAL APPROA...

Abstract Iron deficiency in human diet is a serious problem leading, among others, to the development of iron-dependent anaemia, which affects 1.8 billion people worldwide. Biofortification crop plants, including edible sprouts, promising strategy for combating dietary deficiencies. The aim present study evaluation effect seeds imbibition FeCl 2 solution with Fe at concentrations 100 and 500 mg...

Background & Aims of the Study: The objective of this study was to investigate the seed pre-treatment with salicylic acid (SA) on tolerance and remediation ability of Brassica oleracea var. acephala under lead and zinc stresses. Materials and Methods: Present study was conducted to evaluate phyto-accumulative ability of Brassica oleracea var. acephala in heavy metal concentrat...

Abstract The experiments were conducted in the Laboratory of Tissue culture/Department Forestry/College Agriculture and Forestry/the University Mosul. To propagate three citrus rootstocks (Citrus aurantium L., Citrumelo swingle , Cariso 35 (C35))In vitro . During Initiation stage, single nodes planted on a solid MS medium supplemented with five concentrations BA (0, 1, 2, 3, 4 mg L -1 ). After ...

butachlor (n-(butoxymethyl)-2-chloro-n-2, 6-diethylacetanillide) is widely used chloroacetanilide herbicide in asian region, especially in the north of iran. several studies have been reported on toxicity of butachlor, but little information is accessible on dna damaging potential. thus, the present study was undertaken to investigate of dna damage by butachlor in cyprinuscarpio(pisces: cyprini...

in this study, rainbow trout (oncorhynchus mykiss) eggs were treated with effective doses of  daenensis thyme, thymus daenensis (20, 10 and 5 mgl-1) and mentha, mentha longifolia (10, 5 and 2.5 mgl-1), during incubation period (20 days) until hatching for 30 minutes per every other day as constant flow bath treatment method. the mortality level in normal control (without any treatment) was sign...

the objective of this study was to investigate the propensity of permethrin (ptn) to induce oxidative stress and changes in enzyme activities in liver of rainbow trout and its possible attenuation by vitamin c. forty-eight fish were randomly assigned to 1 of 6 treatment groups and their livers were used for liver perfusion method: control (0 μgl-1 permethrin and 0 mgl-1 vitamin c), ptn-0.16 (0....