The biological relevance of the perforin and Fas ligand (FasL) cytolytic pathways of CD8(+) T lymphocytes (CTL) for cancer immunotherapy is controversial. We investigated the importance of these pathways in a murine renal cell carcinoma expressing influenza viral hemagglutinin as a defined surrogate antigen (Renca-HA). Following Renca-HA injection, all FasL-dysfunctional FasL(gld/gld) mice (n =...

H-2-1inked lr genes, which regulate the virus-specific responsiveness of cytotoxic H2K or D restricted T cells, have the following characteristics: they are virusand H-2specific. They act on cytotoxic T cells directly, but probably not on conventional T helper cells, since in all mouse strains responsiveness restricted to either K or D is high. Low responsiveness is quantitative, not qualitativ...

An experiment was conducted as randomized complete block design with three replications and 14 fertilizer treatments in year 2014. The treatments were including the control, application of chemical fertilizers according the soil analysis, application of 15, 30 and 45 tons of municipal  waste compost per ha as simple and with 25, 50 and 75% of chemical fertilizers. The results revealed that the ...

Lymphohematopoiesis, cell matrix adhesion, homing of leukocytes, T cell activation, and tumor metastasis are mediated through the CD44 family of cell surface receptors. We have recently shown that anti-CD44 mAb trigger protein tyrosine kinase-dependent activation of T cell effector functions. Here, we show that hyaluronate (HA), a CD44 ligand, in conjunction with CD3/TCR-mediated stimuli, is co...

The experiment was carried out to investigate the effect of nutrient combinations and spacing on growth performance mungbean (BARI mung 5) using split plot design. comprised 3 levels spacing; S1- 20 cm × 10 cm, S2- 30 S3- 45 15 cm; 6 fertilizers; F0- Control (without fertilizer), F1- Recommended dose NPK, F2- 5 t ha-1 cowdung, F3- cowdung + F4- 2.5 NPK F5- ha-1cowdung ½ NPK. Among different tre...

Goodman's theorem states that intuitionistic arithmetic in all nite types plus full choice, HA ! + AC, is conservative over rst-order intuitionistic arithmetic HA. We show that this result does not extend to various subsystems of HA ! , HA with restricted induction.

Aim: To study the Long-term impact of soil test and targeted yield based nutrient management on vertical variability in carbon fractions a Vertisol under rice-wheat cropping sequence.
 Place Duration Study: This research trail was conducted during rabi season 2020-21 an on-going programme AICRP STCR initiated 2008 at Research Farm Jawaharlal Nehru Krishi Vishwa Vidyalaya, Jabalpur.
 S...

The activation of soil-fixed phosphorus is a long-term concern in soil science. In order to enhance the activation effect to soil-fixed phosphorus in red soil, different modified zeolite, through physical, chemical method and the associated both physics and chemistry, was used in this paper. The results showed as following: 1) the activated ability to soil-fixed phosphorus in red soil for modif...

Finger millet is extensively cultivated in the tropical and sub-tropical regions of Africa known to save lives small income farmers from starvation at times extreme drought. Therefore, this field experiment was carried out study integrated effect vermicompost inorganic fertilizer blended NPSB with urea on yield components finger millet. Treatments consisted four levels (25, 50, 75, 100%) three ...

Targeting of antigens to immature dendritic cells has been shown to result in antigen-specific T-cell tolerance in vivo. In the INS-HA/TCR-HA transgenic mouse model for type 1 diabetes, we tested the potential of the dendritic cell-specific monoclonal antibody DEC-205 conjugated to the hemagglutinin (HA) antigen (DEC-HA) to prevent disease onset. Whereas untreated INS-HA/TCR-HA mice all develop...