Several modifications that have been made to the NDDO core-core interaction term and to the method of parameter optimization are described. These changes have resulted in a more complete parameter optimization, called PM6, which has, in turn, allowed 70 elements to be parameterized. The average unsigned error (AUE) between calculated and reference heats of formation for 4,492 species was 8.0 kc...

The dose and time dependence of angiotensin II (Ang II) induced hypertension and structural vascular changes and the effect of dietary sodium supplementation on these relationships were investigated. Male Sprague-Dawley rats were treated with 50, 100, or 200 ng . kg-1 . min-1 Ang II subcutaneously for 4 or 12 weeks on normal sodium diet (0.7% NaCl) or with 50 ng . kg-1 . min-1 Ang II SC for 12 ...

Based on the accurate color excess $E_{\rm G_{BP},G_{RP}}$ of more than 4 million stars and NUV,G_{BP}}$ 1 from \citet{2021ApJS..254...38S}, distance extinction molecular clouds in MBM catalog at $|b|>20^{\circ}$ are studied combination with measurement \emph{Gaia}/EDR3. The as well is determined for 66 clouds. ratio G_{BP},G_{RP}}/E_{\rm derived 39 them, which obviously larger implies small pa...

BACKGROUND The Transtheoretical Model suggests that individuals vary according to their readiness to change behavior. Previous work in smoking cessation and other health areas suggests that interventions are more successful when they are tailored to an individual's stage of change with regards to the specific behavior. We report on the performance of a single-item measure ("Ladder") to assess t...

Vol. 26 No. 5, 2014 649 Received August 28, 2013, Revised September 28, 2013, Accepted for publication October 5, 2013 Corresponding author: Bong Seok Shin, Department of Dermatology, Chosun University Hospital, 365 Pilmun-daero, Dong-gu, Gwangju 501-717, Korea. Tel: 82-62-220-3130, Fax: 82-62-222-3215, E-mail: [email protected] This is an Open Access article distributed under the terms of th...

Background and Aims: Tomato yellow leaf curl virus (TYLCV) is one of the most destructive viruses of tomato that leads to reduced tomato yield up to 100% in tropical and subtropical regions. In this study, the complete sequence of TYLCV isolate from Hormozgan province, Iran and its recombination evsent was determined. Methods: TYLCV infected tomato was collected from Hormozgan province. Total D...

This work demonstrates the potential utility of ferrate(VI)-based advanced oxidation processes for degradation a representative UV filter, BP-4. The operational parameters oxidant dose and temperature were determined with kinetic experiments. In addition, effects water constituents including anions (Cl−, HCO3−, NO3−, SO42−), cations (Na+, K+, Ca2+, Mg2+, Cu2+, Fe3+), humic acid (HA) investigate...

Inactivation of the human DNA repair protein, O6-alkylguanine-DNA-alkyltransferase (AGT), by exposure to O6-benzylguanine leads to a dramatic enhancement in the cytotoxic response of cells to chemotherapeutic alkylnitrosoureas. Benzylated pyrimidines identified as more potent inactivators than O6-benzylguanine in vitro include 2,4-diamino-6-benzyloxy-5-nitrosopyrimidine (5-nitroso-BP) and 2,4-d...

Hypertension is associated with reduced cerebral blood flow (CBF). Intensive (<130/80 mm Hg) blood pressure (BP) lowering in older people might give greater reduction in cardiovascular risk, but there are concerns that this might produce hypoperfusion which may precipitate falls and possibly stroke. We determined the effect of intensive compared with usual BP lowering on CBF in hypertensive old...