A little over eighteen months ago, the Genomic Standards Consortium (GSC), with the support of the Michigan State University Foundation and the U.S. Department of Energy launched Standards in Genomic Sciences (SIGS). It was a bold experiment in open access publishing that was undertaken to fill a set of unmet needs within the broad community of genome biologists and bioinformaticians. It sought...

Management systems influence soil quality over time. A randomized block design in 2 (tillage system) 3 (crop rotation) factorial arrangement was laid-out to evaluate the impact of tillage and crop rotation (2002–2007) on soil quality. Conventional tillage and No-till were factored into continuous corn, corn–soybean, and corn–soybean–wheat–Cowpea systems. Ten soil cores were collected at 0–7.5, ...

The carotenoid content of fresh, commercially canned and frozen samples of two cultivars, White Shoepeg (WS) and Golden Whole Kernel (GWK) corn (Zea mays), from the same production field was studied. WS and GWK corn samples were harvested daily over a five-day-period and randomly selected for analysis as fresh, frozen or canned. Major carotenoids detected were lutein and zeaxanthin, and to a le...

Due to climate changes, we encounter irregular and low rainfall. It is important effectively use groundwater select crops that can be grown with deficit irrigation in the summer period. Restricted reduces water consumption but it may cause losses terms of yield quality. Different agronomic practices used minimize these losses. One application foliar zinc fertilizer. In previous studies, was fou...

Transcription factors are important targets for the treatment of a variety of malignancies but are extremely difficult to inhibit, as they are located in the cell’s nucleus and act mainly by protein-DNA and protein-protein interactions. The transcriptional regulators Id1 and Id3 are attractive targets for cancer therapy as they are required for tumor invasiveness, metastasis and angiogenesis. W...

Chronic kidney disease (CKD) affects the nonrenal clearance of drugs by modulating the functional expression of hepatic drug– metabolizing enzymes and transporters. The impact of CKD on oxidative and conjugative metabolism has been extensively studied. However, its effect on hepatic drug reduction, an important phase I drug–metabolism pathway, has not been investigated. We aimed to assess the e...

Sulfur segregation to the surface poses a perplexing problem in basic research on low surface area nickel materials. In addition sulfur effectively poisons catalytic reactions involving CO adsorption on nickel as well as other transition metal catalysts in technically important processes such as methanation and Fischer-Tropsch synthesis. It is not surprising then that considerable attention has...