Clinical and laboratory findings of chronic myelocytic leukemia (CML) were analyzed by means of two different methods; first, retrospective analysis of hematologic data from 16 patients whose laboratory examinations had been performed twice a year for 5-10 yr prior to the development of CML and whose diagnosis was made in a very early stage of the disease, and, second, analysis of hematologic d...

In the present study effects of different levels of probiotic Pediococcus acidilactici, on growth performance and survival rate of Rutilus kuttum were investigated. Fingerlings Kutum with mean weight of 1±0.235 g were reared for 8 weeks in 500-l fiberglass tanks (15 fish per tank) with 4 diet treatments (with 3 replicates for each treatment). Treatments were included 1× 109 , 2:1×109 , 3× 109 C...

Background: Tetanus caused by clostridium tetani, despite being a preventable disease, is still posing significant health hazard to developing countries like Pakistan. Objective: To determine in-hospital mortality among patients of severe adult tetanus presenting with bad prognostic factors.Material and Methods: This cross-sectional study was conducted at the Department Medicine, Medical Teachi...

Many studies show that higher dietary energy density is associated with greater body weight. Here we explored two propositions: i) that child BMI percentile is associated with individual differences in children's relative preference for energy-dense foods, ii) that child BMI percentile is associated with the same individual differences between their parents. Child-parent dyads were recruited fr...

Sepsis is a life-threatening condition that requires urgent care. Thus, the identification of specific and sensitive biomarkers for its early diagnosis and management are of clinical importance. The alarmin prothymosin alpha (proTα) and its decapeptide proTα(100-109) are immunostimulatory peptides related to cell death. In this study, we generated bacterial models of sepsis in mice using two Kl...

Abnormal expression of aquaporins (AQPs) has been reported in several human cancers. Epidermal growth factor receptor (EGFR)-extracellular signal-regulated kinases1/2 (ERK1/2) are associated with tumorigenesis and cancer progression and may upregulate AQPs expression. In this study, we investigated acquaporin-8 expression and signaling via epidermal growth factor receptor-extracellular signal-r...

PURPOSE We studied the association between admission white blood cell (WBC) count and short term outcome in patients with acute cerebral infarction. METHODS 2808 patients with acute cerebral infarction were included in the study. WBC count and other variables were collected within the first 24 hours of admission. Clinical outcomes (death or dependency) were evaluated by neurologists during ho...