Background: β-thalassemia is a common autosomal recessive disorder resulting from over 200 different mutations of beta globin genes. The aim of the present study was to identify the distribution and frequency of the most common β-thalassemia mutations among the population of Isfahan Province in central Iran. Methods: The data presented here were derived from a total of 114 β-thalassemia chromos...

Abstract C 32 H 22 Br 2 CoN 4 O , monoclinic, P 1 / c (no. 4), a = 6.5529(11) Å, b 24.375(4) 18.379(3) β 97.491(3)°, V 2910.6(8) Å 3 Z 4, R gt ( F ) 0.0404, wR ref 0.1268, T 296(2) K.

BACKGROUND We investigated whether Body Mass Index (BMI) at 11 years old has a direct effect on bone mass at age 18 operating through alterations to bone growth and development, or whether the association is mediated by concurrent BMI, fat mass (FM), and fat free mass (FFM). METHODS Path analysis was used to explore the association between BMI at age 11 and whole-body bone mineral content (BM...

Canthaxanthin is a carotenoid that lacks pro-vitamin A activity but is known to have antioxidant activity. The products of its oxidation in oxygen were found to be mainly substituted apo-carotenals and apo-carotenones. The product profile resembles that obtained in the oxidation of β-carotene, except that with canthaxanthin these products are the 4-oxo-β-apo-carotenals and 4-oxo-β-apo-carotenon...

The microstructure and mechanical properties of as-homogenized Mg-xLi-3Al-2Zn-0.2Zr alloys (x = 5, 7, 8, 9, 11 wt.%) were studied. As the Li content increased from 5 wt.% to wt.%, alloy matrix changed α-Mg single-phase α-Mg+β-Li dual-phase then β-Li single-phase. Homogenized With increase in content, strength decreased while elongation increased, corresponding fracture mechanism cleavage microv...

The central β-lactam ring of the title compound, C(23)H(21)NO(3), is almost planar (r.m.s. deviation = 0.032Å). The meth-oxy-benzene ring is almost coplanar with the β-lactam ring [dihedral angle = 1.87 (11)°], whereas the tolyl ring is almost normal to it [75.73 (12)°]. The dihedral angle between the β-lactam ring and the O-bonded phenyl ring is 51.95 (12)°. An intra-molecular C-H⋯O inter-acti...

Multidrug-resistant and difficult-to-treat Acinetobacter baumannii may be responsible for nosocomial infections. The production of carbapenem-hydrolyzing class D β-lactamases (CHDLs) and extended-spectrum β-lactamase (ESBLs) of the GES type possessing a carbapenemase activity has been increasingly reported worldwide in A. baumannii. The aim of this study was to analyze the resistance mechanisms...

Different plant parts of Ligusticopsis wallichiana (family: Apiaceae) are widely used as traditional medicines. Although many volatile constituents are already identified from the leaves of L. wallichiana, there is no detailed report on the nonvolatile constituents. In the present study, we aimed to isolate and identify the major chemical constituents from the leaves. Bhutkesoside A (1), falcar...