BACKGROUND Fidaxomicin is a macrocyclic antibiotic approved in 2011 by the US Food and Drug Administration for treatment of Clostridium difficile-associated diarrhoea (CDAD). OBJECTIVE Herein, we present an epidemiological method to estimate, on a case mix basis, and from the perspective of the US health system, the warranted (justifiable) price per day for fidaxomicin, as a percent of the wh...

purpose: to design and manufacture iodine 125 radioactive plaques which can be used in patients with ocular melanoma, and to evaluate the efficacy of plaques in an animal model. methods: this prospective basic study was performed in collaboration with farabi hospital and tehran atomic energy agency. the iodide 125 plaques were designed and manufactured based on the collaborative ocular melanoma...

we report a case of florid polypoid endometriosis presenting with advanced bulky disease in pelvis with serum ca – 125 levels of 7844u/ml. the extent of tumor, ct scan findings, elevated serum ca – 125 levels were suggestive of ovarian malignancy. histopathology demonstrated endometrial glands and stroma. glands were neither crowded nor complex and were separated by a fibromatous stroma that co...

in this study, the performance of aquacrop model to predict yield production of winter wheat (roshan and gods varieties), water and solute balance of soil profile was evaluated under water and salinity stresses. field experiments were conducted with three levels of saline irrigation water including: s1, s2 and s3corresponding to 1.4, 4.5 and 9.6 ds/m, respectively, and four levels of irrigation...

Electrolyte abnormalities are common in emergency medicine and can vary greatly in importance, severity, and symptoms. Asymptomatic electrolyte abnormalities can usually be gradually corrected, but those that cause alterations in consciousness or lifethreatening dysrhythmias require immediate therapy to avoid permanent sequelae or death. In some cases, therapy for lifethreatening electrolyte di...

Jackson, Donald C., Carlos E. Crocker, and Gordon R. Ultsch. Bone and shell contribution to lactic acid buffering of submerged turtles Chrysemys picta bellii at 3°C. Am J Physiol Regulatory Integrative Comp Physiol 278: R1564– R1571, 2000.—To evaluate shell and bone buffering of lactic acid during acidosis at 3°C, turtles were submerged in anoxic or aerated water and tested at intervals for blo...

The calibration of a liquid I-125 source in an older standard dose calibration system is presented. The calibration factor agrees well with factors established by the NIST for newer dose calibration systems. The determination of the source activity is necessary to accurately calculate the time required to deliver the prescribed dose.