Artificial ecotopes of 121 peridomiciliary environments in four rural localities in the state of Ceará, Brazil, were studied and the type of material of the ecotopes was identified as triatomine infestation. Two thousand two hundred and four Triatoma brasiliensis Neiva, 340 Triatoma pseudomaculata Corrêa and Espínola, 121 Rhodnius nasutus Stall, and 5 Panstrongylus lutzi (Neiva and Pinto) were ...

BACKGROUND This study investigated the cardiovascular (CV) safety profile of the dipeptidyl peptidase (DPP)-4 inhibitor linagliptin versus comparator treatments. METHODS This was a pre-specified meta-analysis of CV events in linagliptin or comparator-treated patients with type 2 diabetes mellitus (T2DM) from eight Phase 3 studies. All suspected CV events were prospectively adjudicated by a bl...

The impacts of thyroid hormones (TH) on lipid profile in euthyroid adults have gained much attention. It is currently unknown whether BMI influences such interaction. In the present study, we investigate the role of BMI in modulating the association between TH and lipid parameters in 1372 euthyroid healthy adults. Our results show that thyroid parameters are differentially associated with lipid...

Farrar, W. Edmund, Jr. (Walter Reed Army Institute of Research, Washington, D.C.), Laurence M. Corwin, and Thomas H. Kent. Mitochondrial fatty acid oxidation and susceptibility to endotoxin in acute liver injury. J. Bacteriol. 90:1365-1372. 1965.-Acute liver injury was produced in guinea pigs with three chemically unrelated hepatotoxins: CCl(4), allyl alcohol, and dl-ethionine. The effects of t...

OBJECTIVE In euthyroid individuals, autoantibodies to thyroid peroxidase (TPOab) and thyroglobulin (Tgab) are regarded as early markers of thyroid autoimmunity. Family and twin studies suggest that development of thyroid autoantibodies in first-degree relatives of patients with autoimmune thyroid disease is under genetic influence. We aimed to estimate the relative importance of genetic and env...

For responsible fisheries management of threatened species, it is essential to know the composition of catches and the extent to which fisheries exploit weak wild populations. The threatened Estonian, Finnish and Russian sea trout populations in the Gulf of Finland are targets of mixed-stock fisheries. The fish may originate from rivers with varying production capacities, from different countri...

The temporal and tissue-specific actions of estrogen are mediated by estrogen receptors and . The ERs are steroid hormone receptors that modulate the transcription of target genes when bound to ligand. The activity of these transcription factors is regulated by a variety of factors, including ligand binding, phosphorylation, coregulators, and the effector pathway (ERE, AP1, SP1). The end result...

Skin cancer is one of the major types of cancers and its incidence has been increasing over the past decades. Skin lesions can arise from various dermatologic disorders and can be classified to various types according to their texture, structure, color and other morphological features. The accuracy of diagnosis of skin lesions, specifically the discrimination of benign and malignant lesions, is...