the measurement of antibody responses of animals exposed to bvdv either through a natural exposure or an immunization protocol is still a standard procedure. for bvdv, the test formats have been largely limited to elisa which is a valuable diagnostic test to measure the level of bvdv specific antibodies as well as antigen in blood samples. in the present study, 120 blood samples were collected ...

background: hydatidosis is one of the most important helminthic diseases causing serious health and economic problems in many countries including iran. currently available diagnostic approaches for diagnosis of cystic echinococcosis (ce) are not satisfactory since they have not achieved a reasonable validity in diagnosis of ce. this study aimed to assess the perform¬ances of western blotting (w...

Background and Aims: Influenza is an acute respiratory illness that is caused by a virus belonging to Orthomyxoviridae family. This virus spreads rapidly every year in cold season and leads to morbidities and mortalities especially in adults and children, which causes billions of dollars of economic losses. Accordingly, development of a rapid, sensitive and inexpensive laboratory diagnosis base...

common variable immunodeficiency (cvid) is a heterogeneous heritable disease characterized by arrest in b cell differentiation. an association between cvid and two hla haplotypes, haplotype i (hla-a1, hla-b8, hla-dr3) and haplotype ii (hla-a29, hla-b44, hladr7)has been previously documented. in the present study, we have attempted to find an association between susceptibility to cvid and hla cl...

background: detection of hepatitis c virus specific antibodies is the initial step in chronic hcv diagnosis.  hcv ns4b is among the most immunogenic hcv antigens and has been widely used in commercial enzyme immunoassays (eia). additionally, ns4b, a key protein in the virus replication, can be an alternative target for antiviral therapy.objectives: development of a new method for high-level exp...

human fascioliasis due to unknown species and animal fascioliasis caused by both or one of fasciola spp. are commonly seen in iran. to compare electrophoretic patterns of somatic and excretory-secretory antigens of f. hepatica and f. gigantica  by sodium dodecyl sulphate polyacrylamide gel electrophoresis (sds-page), the adult flukes were collected from infected slaughtered bovine livers. e/s a...

we describe a 16 year old boy with acne fulminans associated with axial and peripheral polyarthritis. the patient's clinical course and therapy with isotretinoin, prednisolone and oxytetracycline are described. a possible association between the presence of hla -b 27 antigen and reactive arthritis with acne fulminans in this case is evaluated. a review of the literature is included.

background: myelodysplastic syndrome is a mixed clonal disorder of bone marrow progenitor cells. understanding the pattern of the different lineage-specific, immature, and mature markers in myelodysplastic syndrome will help in setting-up the frame of reference to diagnose. patients and methods: we compared 60 bone marrow samples from 30 newly-diagnosed patients with myelodysplastic syndrome an...

background: regarding that accurate diagnosis of human hydatidosis still needs more investigations, the present study was conducted to clone, express, and evaluate the gene encoding agb subunits (egagb16 kda) from echinococcus granulosus (iranian g1 strain) and its evaluation by elisa test. methods: dna was extracted from protoscoleces and was utilized by pcr for strain identification. total rn...

cryptococcosis has become the fourth leading life-threatening opportunistic infection in patients with aids, but also occurs in non-aids patients. in view of the increasing numbers of infection during last decade in iran, use of rapid, sensitive and specific test for diagnosis of cryptococcal disease has become important than ever. we aimed to produce the reagents for latex cryptococcal antigen...