ABSTRACT. Benzoylacetone (1) underwent a series of multi-component reactions with aromatic aldehydes and malononitrile or ethyl cyanoacetate to produce the pyran derivatives 4a-f. The latter compounds reacted yield condensation products 5a-m. On other hand, reaction 4a-f either diazonium salts 6a-c yielded arylhydrazone 7a-i. adehydes cyclohexan-1,3-dione produced 9a-c. Compound 1 Gewald’s elem...

In this study appropriate hydrazide compounds, furan-2-carboxylic acid hydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substituted thiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10. The 1,4-substituted thiosemicarbazides were then converted into 5-(furan-2-yl or benzyl)-4-(aryl)-4H-1,2,4-triazole-3-thiols 8a-e and...

A simple, efficient, and green practical approach to Knoevenagel condensation of malononitrile and different aldehydes has been developed using an ionic liquid functionalized on Fe3O4 magnetic nanoparticles as heterogeneous catalyst. This nanostructural catalyst has also been applied for the synthesis of 4H-benzo[b]pyran derivatives in water at room temperature in short reaction time. All of th...

The structural motif that results from the fusion of a benzene ring to a heterocyclic pyran ring, known as chromene, is broadly found in nature and it has been reported to be associated with a wide range of biological activity. Moreover, asymmetric organocatalysis is a discipline in expansion that is already recognized as a well-established tool for obtaining enantiomerically enriched compounds...

A series of MOFs constructed from 5-((carboxymethyl)amino)isophthalic acid (H 3 cmai) have been prepared and characterised, with [Cd (cmai) 2 O) 4 ]·4H O demonstrating loss water in a single-crystal-to-single-crystal transformation.