quantitative serum level measurements of gc , cp , c3 , igg , iga and 1gm were carried out on 102 patients with esophageal carcinoma following laryngectomy, in comparison with 66 healthy individuals as controls, in gonbad area, north east of iran. the procedure of radioinimuno-diffusion by standard m partigen plates was used for the measurements. a significant decrease was observed in gc level ...

antigenicity of proteins found in cow's milk is age dependent. this is primarily due to infants possessing a more permeable intestinal wall than that in adults. thus infants may acquire cow's milk allergy during their first year of life. while milk antigen specific ige may cause allergy in susceptible subjects, there is some evidence indicating that milk antigen specific igg may play some role ...

background and objectives:   iranian chronic hbv carrier’s population has shown a unique pattern of genotype d distri- bution all around the country. the aim of this study was to explore more details of evolutionary history of carriers based on structural surface proteins from different provinces. materials and methods: sera obtained from 360 isolates from 12 different regions of country were u...

Viral particles at the late stages of SV40 morphogenesis were examined for the presence of HMG proteins 1 and 2, by an lmmunochemical method involving the transfer of proteins from polyacrylamide gels to nitrocellulose membranes. It was found that these proteins are present in SV40 provirions, in which histone HI is still associated with viral chromatin, but absent in mature SV40 virions. INTRO...

Analysis of (35)S-methionine-labeled extracts of adenovirus 2-infected KB cells revealed 22 virus-induced polypeptide components. Most proteins of the virion were easily detected in extracts of whole cells labeled for short periods between 15 and 30 h after infection; however, several virion components were conspicuously absent. Radioactivity appeared in two of these virion components during a ...

Bcl-2 family proteins are key intracellular regulators of programmed cell death. Several recent discoveries demonstrate how these proteins interact with the molecular machinery that controls and executes the cell-death programme, and how they can themselves be regulated by extracellular survival signals.

HMG1 and 2 (high mobility group proteins 1 and 2; renamed HMGB1 and 2) contain two DNA-binding HMG-box domains (A and B) and a long acidic C-terminal domain. They bind DNA without sequence specificity, but have a high affinity for bent or distorted DNA, and bend linear DNA. The individual A and B boxes (which, although broadly similar, show both structural and functional differences) exhibit ma...

This review informs about the chemical composition of plasma proteins majorly albumin and globulin. Blood proteins, also called are found in blood plasma. While, serum present human body very high quantities for other proteins. Hundreds dissolved but only two major protein groups i.e. Albumin Globulin. is a important component (55% proteins) it made by liver. There an immediate correlation betw...

The bcl-2 family of proteins play an important role in the control of apoptosis. Family members exist which are either pro- or anti-apoptotic and their activity appears to control a checkpoint between signals from the cell surface and activation of the ICE-family of proteases. Despite having a key role to play in apoptosis, the mechanism of action of these proteins can only, at present, be infe...

There is considerable current interest in molecules that bind intra- or extracellular protein surfaces and inhibit protein-protein interactions. Previously we have reported that miniature proteins based on pancreatic-fold polypeptides can recognize even shallow alpha-helix binding clefts with high affinity and selectivity against unrelated proteins. One such miniature protein, PPBH3-1, binds th...