Abstract Background Diabetes mellitus (DM) could be classified as type 1 diabetes (T1DM), 2 (T2DM), gestational (GDM) and others according to etiology pathology. Diabetic nephropathy (DN) is one of the most serious complications DM. YKL-40 a marker inflammation some studies have indicated that DM was related with inflammation. The objective our study perform systematic review meta-analysis conf...

For a d-dimensional quasi-Monte Carlo method with n points, calculating the weighted L 2 discrepancy using a formula obtained directly from its deenition requires O(2 d?1 dn 2) operations. Here we give an alternative formula requiring O(dn 2) operations. We also present the rst numerical calculations of the weighted L 2 discrepancy. These results give supporting evidence for thèlimiting discrep...

To examine the role of bone morphogenetic protein (BMP) signaling in chondrocytes during endochondral ossification, the dominant negative (DN) forms of BMP receptors were introduced into immature and mature chondrocytes isolated from lower and upper portions of chick embryo sternum, respectively. We found that control sternal chondrocyte populations expressed type IA, IB, and II BMP receptors a...

BACKGROUND Diabetic nephropathy (DN), especially type 2 diabetes, is now increasing rapidly worldwide, also in Asian countries, and is one of the major long-term vascular complications. The pathogenesis of DN involves both genetic and environmental factors. Around 30-40% of type 2 diabetic patients develop DN despite strict blood glucose and/or blood pressure control. Although it is considered ...

Objective This study aimed to evaluate how leucine are associated with diabetic nephropathy (DN) in type 2 diabetes (T2D) patients and the gender difference of this association. Methods We retrieved 1,031 consecutive T2D who meet inclusion exclusion criteria from same tertiary care center extracted clinical information electronic medical record. Plasma was measured by liquid chromatography-mass...

Diabetic nephropathy (DN) is a leading cause of end-stage kidney disease nowadays. Certain cancers are more common in patients with diabetes mellitus. However, there are no data concerning the cancer pattern in patients with DN. The aim of this study is to investigate the site-specific cancer risk and mortality in these patients.A retrospective cohort study of 5643 DN patients between 2000 and ...

BACKGROUND/AIMS We have previously associated SNP 894G>T in the NOS3 gene with diabetic nephropathy (DN) using multi-locus analysis. Variant 894G>T has been widely studied as a DN susceptibility factor with contradictory results. In the present study we genotyped 894G>T in the cohort of prospectively followed type 2 diabetics with the aim to investigate its possible role in the progression of D...

This paper models a biological brain—excluding motivation (e.g., emotions)—as a Finite Automaton in Developmental Network (FA-in-DN), but such an FA emerges incrementally in DN. In artificial intelligence (AI), there are two major schools: symbolic and connectionist. Weng 2011 [1] proposed three major properties of the Developmental Network (DN) which bridged the two schools: 1) From any comple...