Agouti is a paracrine-acting, transient antagonist of melanocortin 1 receptors that specifies the subapical band of yellow on otherwise black hairs of the wild-type coat. To better understand both agouti structure/function and the germline damage caused by chemicals and radiation, an allelic series of 25 recessive, homozygous-viable agouti mutations generated in specific-locus tests were charac...

Canadian Forest Service (Pacific Forestry Centre), Natural Resources Canada, 506 West 18 Burnside Road, Victoria, British Columbia, V8Z 1M5, Canada 19 20 21 22 23 24 25 Pre-print of published version. Reference: Bolton, D.K., N.C. Coops, and M.A. Wulder. (2013). Measuring forest structure along productivity gradients in the Canadian boreal with small-footprint Lidar. Environmental Monitoring an...

of suicidal ideationwas established in a patient sample seekingemergency treatment fornon-psychiatric reasons. Using a computerisedmentalhealth screeningpanel, datawere collected from waiting-roompatients duringrandomised shifts over a 45-dayperiod. Of1590 screenedpatients,185 (11.6%) acknowledged suicidal ideation and 31 (2%) reportedplanning tokill themselves. Almost all of thosewith suicidal...

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 701 6.4 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 630 5.7 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 651 5.9 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 634 5.8 20 to 24 years . . . . . . . . . . . . . . . . . . . . ....

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 180 8.1 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150 6.7 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187 8.4 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 8.3 20 to 24 years . . . . . . . . . . . . . . . . . . . . ....

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 4.8 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 158 7.6 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 206 9.9 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 8.9 20 to 24 years . . . . . . . . . . . . . . . . . . . . ....

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 165 6.8 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154 6.3 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185 7.6 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192 7.9 20 to 24 years . . . . . . . . . . . . . . . . . . . . ....

The human leukocyte antigen (HLA) alleles are extremely polymorphic among ethnic population and the peptide binding specificity varies for different alleles in a combinatorial manner. However, it has been suggested that majority of alleles can be covered within few HLA supertypes, where different members of a supertype bind similar peptides, yet exhibiting distinct repertoires. Since the overla...

In this report, we describe the sequence allelotyping of the Ha-ras variable number tandem repeat (VNTR) region using a minisatellite variant repeat (MVR)-PCR approach. This method permits the rapid identification of internal sequence variations among the VNTR alleles, exploiting the presence of two polymorphic sites within the 28-bp repeat subunits that give rise to four distinct repeat types....

Many recessive genetic disorders are found at a higher incidence in people of Ashkenazi Jewish (AJ) descent than in the general population. The American College of Medical Genetics and the American College of Obstetricians and Gynecologists have recommended that individuals of AJ descent undergo carrier screening for Tay Sachs disease, Canavan disease, familial dysautonomia, mucolipidosis IV, N...