نتایج جستجو برای: 2525 target
تعداد نتایج: 398670 فیلتر نتایج به سال:
introduction: attention to rural development than urban development in the third world not because of the majority of the population in rural areas, but also because it is the final solution to the problem of urban unemployment and decreasing the population density metropolis, development and improvement of the rural environment. rural tourism potentially can be considered as fundamental approa...
this study aims to design some dual-target anticancer candidates, capable to act as an alkylating agent as well as a thymidylate synthase (ts) inhibitor. the designed scaffold is a combination of nucleobase, amino acid and aziridine structures. the candidates are docked into ts and three dna double strand structures and evaluated based on their binding interaction energies and ligand efficienci...
there is undoubtedly general agreement that the efficiency of educational investments should he maximized through the managerial process as far as possible. agricultural extension is one of the crucial tasks in developing agricultural societies calling for considerable consumption of intellectual investment. the management of agricultural extension projects (aeps) however, needs careful pla...
different treatment strategies of alzheimer's disease (ad) are being studied for treating or slowing the progression of ad. many pharmaceutically important regulation systems operate through proteins as drug targets. here, we investigate the drug target proteins in beta-amyloid (aβ) injected rat hippocampus treated with lavandula angustifolia (la) by proteomics techniques. the reported stu...
Head and neck cancer patients presenting with distant metastases are generally considered incurable. Treatment patterns and survival by primary disease site and therapy have not been described. Retrospective cohort analysis of 2525 patients in the National Cancer Database (2003-2006). Kaplan-Meier and Cox proportional hazards analyses were performed. Combined locoregional and systemic therapy w...
BACKGROUND To understand the relationship between the Staphylococcus aureus infection rate and the reasonable usage of antibiotics, which will help in the effective control of MRSA infection. METHODS All data were obtained by the application of the nosocomial infection surveillance network. Drug resistance, departmental sources, and isolated sites as well as infection rate variations of S. au...
By single crystal NMR the nuclear quadrupole coupling constants eQ,.h~ (H), the asymmetry parameters >/(H) and the dircetion cosines of the principal axes of the electric field gradient tensors of the H atoms of the two kinds of D 2 0 molecules have been determined at 295 K in RbAl(S04)2 • 1 2 D 2 0 . The results show that the D 2 0 molecules surrounding the ion Al + are "static" within the ...
The proximal region of chromosome 15 is one of the genomic hotspots for copy number variants (CNVs). Among the rearrangements observed in this region, CNVs from the interval between the common breakpoints 1 and 2 (BP1 and BP2) have been reported cosegregating with autism spectrum disorder (ASD). Although evidence supporting an association between BP1-BP2 CNVs and autism accumulates, the magnitu...
OBJECTIVE To characterise the nature of the sport injury prevention literature by reviewing published articles that evaluate specific clinical interventions designed to reduce sport injury risks. DATA SOURCES PubMed, Cinahl, Web of Science and Embase. MAIN RESULTS Only 139 of 2525 articles retrieved met the inclusion criteria. Almost 40% were randomised controlled trials and 30.2% were coho...
This contribution addresses filtering requirements to meet the ETSI and ANSI specifications on transmit signal power spectral density (PSD) for VDSL systems employing multicarrier modulation techniques. It is shown that the specifications can be met with simple fixed filtering elements. Conformance with the various PSD masks is achieved by proper adjustment of the digital gains at the input of ...
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