Neuroactive testosterone metabolites synthesized by enzymes 5α-reductase and 3α/3β-hydroxysteroid oxidoreductase are critical physiological modulators of the central nervous system (CNS) function. Indeed, as discussed in this review, they exert a variety effects on myelination, brain maturation, neurotransmission, reproductive behavior, stress responses. The expression synthesis these well leve...

Hypoxia-inducible transcription factors (HIF) form heterodimeric complexes that mediate cell responses to hypoxia. The oxygen-dependent stability and activity of the HIF-α subunits is traditionally associated to post-translational modifications such as hydroxylation, acetylation, ubiquitination, and phosphorylation. Here we report novel evidence showing that unsaturated fatty acids are naturall...

It was shown by James Tung in 2005 that if a sequence Z = {zn} of points in the complex plane satisfies inf n6=m |zn − zm| > 2/ √ α, then Z is a sequence of interpolation for the Fock space F p α . Using results from circle packing, we show that the constant above can be improved to √ 2π/( √ 3α), which is strictly smaller than 2/ √ α. A similar result will also be obtained for sampling sequences.