3 4 dihydropyrimidine

نتایج جستجو برای: 3 4 dihydropyrimidine

تعداد نتایج: 2481797 فیلتر نتایج به سال:

A phase I study of S-1 administration and a 24-h infusion of cisplatin plus paclitaxel in patients with advanced gastric cancer.

Journal: :Anticancer research 2006

Hiroaki Iwase Masaaki Shimada Tomoyuki Tsuzuki Masayuki Okeya Keiko Kobayashi Yuichi Hibino Hisanori Watanabe Hidemi Goto

OBJECTIVE The objective of this study was to determine the dose-limiting toxicity (DLT), the maximum tolerated dose (MTD), the recommended dose (RD) and the preliminary antitumor activity of S-1, oral dihydropyrimidine dehydrogenase inhibitory fluoropyrimide, in combination with cisplatin and paclitaxel for advanced gastric cancer. PATIENTS AND METHODS Paclitaxel was administered on day 1. A ...

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4-[(4-Amino-3-pyridyl)iminomethyl]benzonitrile

Journal: :Acta Crystallographica Section E Structure Reports Online 2008

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3-(4-Bromophenyl)quinazolin-4(3H)-one

Journal: :Acta Crystallographica Section E Structure Reports Online 2011

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Expression of thymidine phosphorylase and dihydropyrimidine dehydrogenase in human breast carcinoma cells and tissues.

Journal: :Anticancer research 2009

Wings T Y Loo Louis W C Chow Takashi Suzuki Katsuhiko Ono Takanori Ishida Hisashi Hirakawa Noriaki Ohuchi Hironobu Sasano

BACKGROUND The therapeutic effects of oral capecitabine are proposed to be determined by the equilibrium of two intratumoral metabolizing enzymes, namely thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD). The present study aims to evaluate this hypothesis by in vivo experiments and immunohistochemical analysis in 31 cases of human breast carcinoma. MATERIALS AND METHODS T...

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