BACKGROUND Oral sucrose (75 g) ingested 40 minutes before exercise improves exercise tolerance in McArdle disease. OBJECTIVE To determine whether a lower dose of sucrose administered closer in time to exercise could have a similar beneficial effect on exercise capacity in patients with McArdle disease. DESIGN Placebo-controlled crossover. SETTING Neuromuscular Research Unit at the Departm...

An in vitro technique is described for assessing the chemotactic activity of soluble substances on motile cells. Antibody-antigen mixtures when incubated (37 degrees C) in medium containing fresh (i.e. non-inactivated) normal rabbit serum exert a strong chemotactic effect on rabbit polymorphonuclear leucocytes. Results are described which indicate that, when antibody-antigen complexes are incub...