The interstitial fluid transport plays an important role in terms of its effect on the delivery of therapeutic agents to the cancerous organs. In this study, a comprehensive numerical simulation of the interstitial fluid transport establishing 3D models of tumor and normal tissue is accomplished. Different shapes of solid tumors and their surrounding normal tissues are selected, by employing th...

This study is concerned with the prediction of particles’ velocity in a dilute turbulent gas-solidboundary layer flow using a fully Eulerian two-fluid model. The closures required for equationsdescribing the particulate phase are derived from the kinetic theory of granular flows. Gas phaseturbulence is modeled by one-equation model and solid phase turbulence by MLH theory. Resultsof one-way and...

This paper presents a new super-element with twelve degrees of freedom for latticed columns. This elements is developed such that it behaves, with an acceptable approximation, in the same manner as a reference model does. The reference model is constructed by using many Solid elements. The cross section area, moments of inertia, shear coefficient and torsoinal rigidity of the developed new elem...

In this paper, we consider scenes that are immersed in transparent refractive media with a dynamic surface. We take the first steps to reconstruct both the 3D fluid surface shape and the 3D structure of immersed scene simultaneously by utilizing distortion and defocus clues. We demonstrate that the images captured through a refractive dynamic fluid surface are the distorted and blurred versions...

In cake filtration processes, where particles in a suspension are separated by forming filter on the medium, resistances of and medium cause specific pressure drop which consequently defines process energy effort. The micromechanics formation (interactions between particles, fluid, other medium) must be considered to describe pore clogging, growth consolidation correctly. A precise 3D modeling ...

We present an in-silico model of avascular poroelastic tumour growth coupled with a multiscale biphasic description of the tumour-host environment. The model is specified to in-vitro data, facilitating biophysically realistic simulations of tumour spheroid growth into a dense collagen hydrogel. We use the model to first confirm that passive mechanical remodelling of collagen fibres at the tumou...

With today’s Virtual Reality (VR) systems, it is difficult to directly and precisely create and modify objects in a VR environment. This chapter presents an approach for solid modelling in a VR environment. Solid modelling in the VR environment is performed precisely in an intuitive manner through constraint-based manipulations. A hierarchically structured and constraint-based data model is dev...

Abstract The effect of the solid–wall boundary condition on the segregation behavior of a sand ternary mixture differing in size but having the same proportion has been investigated in a gas–solid bubbling fluidized bed. A multi-fluid computational fluid dynamics model incorporating the kinetic theory of granular flow has been used. The mass fraction profiles of the different-sized partic...

The complete 3D nonlinear dynamic problem of extensible, flexible risers conveying fluid is considered. For describing the dynamics of the system, the Newtonian derivation procedure is followed. The velocity field inside the pipe formulated using hydrostatic and Bernoulli equations. The hydrodynamic effects of external fluids are taken into consideration through the nonlinear drag forces in var...