We report the development of a new three-dimensional (3D) momentum-imaging setup based on conventional velocity map imaging to achieve the coincidence measurement of photoelectrons and photo-ions. This setup uses only one imaging detector (microchannel plates (MCP)/phosphor screen) but the voltages on electrodes are pulsed to push both electrons and ions toward the same detector. The ion-electr...

Understanding the tumor microenvironment is critical to characterizing how cancers operate and predicting how they will eventually respond to treatment. The mouse window chamber model is an excellent tool for cancer research, because it enables high resolution tumor imaging and cross-validation using multiple modalities. We describe a novel multimodality imaging system that incorporates three d...

In this paper, we report a method for 3D visualization of a biological specimen utilizing a structured light wide-field microscopic imaging system. This method improves on existing structured light imaging modalities by reassigning fluorescence photons generated from off-focal plane excitation, improving in-focus signal strength. Utilizing a maximum likelihood approach, we identify the most lik...

BACKGROUND AND PURPOSE The importance of the anterior choroidal artery (AChA) is related to its supply of crucial anatomic structures, such as the internal capsule. Angiographically, the AChA can be detected in 71% to 98% of patients, but as yet, its visibility on MR images has not been evaluated. Our goal was to assess the sensitivity of MR imaging in the identification of the AChA and its ana...

High-performance intraoperative imaging is essential to an ever-expanding scope of therapeutic procedures ranging from tumor surgery to interventional radiology. The need for precise visualization of bony and soft-tissue structures with minimal obstruction to the therapy setup presents challenges and opportunities in the development of novel imaging technologies specifically for image-guided pr...

During the same MR imaging scan that revealed these findings, we also performed 3D-ASL (3D fast spin-echo acquisition with spiral readout, pseudocontinuous ASL (pCASL); repetition time/effective echo time, 4590/10.5 ms; field of view, 240 × 240 mm2; labeling time, 1450 ms; post-labeling delay, 1525 ms; slice thickness, 4.0 mm; number of slices, 32; and number of excitations, 2) using a 3-Tesla ...

The computer-generated integral imaging system is a way of showing stereoscopic displays that allows users to see 3D images without wearing any special glasses. In the integral imaging system, the 3D object information is stored as elemental images, which are generated by the image mapping method. This paper reviews the previous image mapping methods, such as PRR (Point Retracing Rendering), MV...

After the development of a hand-held intraoperative device for 3D real-time imaging of radioactively labeled sentinel lymph nodes in the human body, we present our first experience with the newest version of the freehand single-photon emission computed tomography (SPECT) technology in the operating room. The freehand SPECT system combines a gamma probe and an optical infrared positioning system...

A compact MRI system for measuring the trabecular bone (TB) microstructure of the finger using a high-field-strength (1.0T) permanent magnet was developed. The entire system was installed in a 0.6 mx1.2 m space. One male and 36 female subjects participated in the imaging experiments. The TB of the distal phalanx of the middle finger was imaged at a voxel resolution of (160 microm)3 using a thre...