Introduction: The multiple flip angle (MFA) [1] and inversion recovery (IR) based methods are two of the widely used techniques to determine T1 values in vivo. To improve acquisition speed, the dual (two) flip angle technique (DAT) with short repetition times is primarily employed while IR followed by Look-Locker acquisitions is employed with inversion recovery schemes. Typically, absolute quan...

Introduction: The reconstruction of images from highly undersampled data, especially for the reconstruction of high frame rate MR Angiography images, has recently become a topic of great interest. Many methods which exploit both the sparse nature of angiographic images as well as the relatively mild undersampling artifacts of the radial trajectory have been introduced, including compressed sens...

INTRODUCTION Radiological examinations, such as abdominal x-ray or CT, during pregnancy have been associated with a slightly increased risk of brain tumor [1]. Radiation exposure during the embryonic period causes various diseases such as hydrocephalus, microcephaly and other brain disorder [2]. Recently, it has been demonstrated that manganese-enhanced MRI (MEMRI), using a MnCl2 contrast agent...

INTRODUCTION Myo-Inositol (MI) is one of the most abundant metabolites (~10mM) visible on proton magnetic resonance spectroscopy (HMRS) of the human brain. MI functions as an osmolyte and its concentration is altered in many brain disorders. MI has shown to be elevated in Alzheimer’s disease, gliomatosis cerebri, renal failure, diabetes mellitus, recovering hypoxia, hyperosmolar states, and pro...

The quest towards higher field strengths such a 3.0 T and 4.0 T has its advantages due to higher SNR values, but also has its downfalls. For 3.0 T and 4.0 T imaging SAR plays a prominent role on determining many crucial parameters like number of slices per acquisition, duration of RF pulses, etc., which can affect the overall scan time of a sequence. Furthermore, when designing transmit and rec...

Introduction: The quantification of local Tissue Sodium Concentration (TSC) levels can serve as a diagnostic measure for renal diseases, because TSC is strongly linked to the corticomedullary function, which regulates the vascular ion concentrations [1, 2]. However, the validation of the achieved TSC quantification accuracy on rat kidneys using quantitative Na Magnetic Resonance Imaging (qNa-MR...

Introduction We have presented MRI volumetric measurement of plaque burden for in vivo evaluation of therapeutic agents for treating atherosclerosis [1]. However, alternative imaging methods that are able to characterize and quantify inflammation levels in animal models of the disease would be more specific and sensitive to disease progression and to the effects of treatment than would volumetr...

The inversion of a composite governing equation for the estimation of a boundary heat flux from ultrasonic pulse data is presented. The time of flight of the ultrasonic pulse is temperature dependent and can be used to predict the boundary heat flux. Sensitivities of the approach are examined, results from fabricated data are presented, and example solutions are provided with actual ultrasonic ...

Objective: In Alzheimer’s disease (AD) some patients present with cognitive impairment other than episodic memory disturbances. We evaluated whether occurrence of posterior atrophy (PA) and medial temporal lobe atrophy (MTA) could account for differences in cognitive domains affected. Methods: In 329 AD-patients we assessed five cognitive domains: memory, language, visuo-spatial functioning, ex...

We describe a model for the lexical analysis of Arabic text, using the lists of alternatives supplied by a broad-coverage morphological analyzer, SAMA, which include stable lemma IDs that correspond to combinations of broad word sense categories and POS tags. We break down each of the hundreds of thousands of possible lexical labels into its constituent elements, including lemma ID and part-of-...