As a cost-effective alternative to large supercomputers, Beowulf clusters are now deployed worldwide to support scientific computing. While Beowulf clusters yield high computing performance, they also pose several challenges: 1) Heat induced hardware failure makes large scale commodity clusters fail quite frequently, 2) Powering all the computer nodes without adapting to the varying work load m...

Cholangiocarcinoma arising in the liver can be classified into intrahepatic (or peripheral) cholangiocarcinoma (ICC) or perihilar cholangiocarcinoma, depending on the topographic location of the tumor along the intrahepatic biliary tree. Grossly, peripheral ICC usually presents as a mass-forming type, while perihilar ICC may present as mass-forming, periductal infiltrating, or intraductal-growt...

The global logic used by the brain for differentially encoding positive and negative experiences remains unknown along with how such experiences are represented by collections of memory traces at the cellular level. Here we contrast the cellular memory traces that form in the dorsal paired medial (DPM) neurons of Drosophila after conditioning flies with odors associated with aversive or appetit...

Phytoalexin biosynthesis is part of the defense mechanism of soybean (Glycine max) plants against attack by the fungus Diaporthe phaseolorum f. sp. meridionalis (Dpm), the causal agent of stem canker disease. The treatment of soybean cotyledons with Dpm elicitor or with sodium nitroprusside (SNP), a nitric oxide (NO) donor, resulted in a high accumulation of phytoalexins. This response did not ...

It was with sorrow that Epilepsy Action learned of the recent death of Dr Tim Betts. Our thoughts and condolences are with his family at this sad time. Dr Betts was a former consultant neuropsychiatrist specialising in epilepsy at the Queen Elizabeth II Hospital in Birmingham. He was also a clinical reader in psychiatry at the University of Birmingham. He led the Birmingham neuropsychiatry serv...

Dr John Hurst’s approach to the treatment of people with intellectual disabilities was ahead of its time. In the early 1970s, John, who has died aged 79, developed the pre-discharge unit at South Ockenden Hospital, Essex, as a therapeutic community, as well as a number of community group homes. He also introduced one of the earliest community nursing services in intellectual disability there be...

DPM is a system for monitoring the execution and performance of distributed programs. An important characteristic of its design is the simplicity of each part of the design. This simplicity has resulted in a system of tools that has a wide range of applications and that was relatively easy to construct. We start with a simple framework for distributed computation based on message interactions. ...

A comprehensive set of measurements and calculations has been conducted to investigate the accuracy of the Dose Planning Method (DPM) Monte Carlo code for dose calculations from 10 and 50 MeV scanned electron beams produced from a racetrack microtron. Central axis depth dose measurements and a series of profile scans at various depths were acquired in a water phantom using a Scanditronix type R...