Four patients with IgG4-related disease (IgG4-RD) showed increased percentages of RP105-negative B cells in the peripheral blood. Case 1: A 66-year-old man having retroperitoneal fibrosis had 18.8% of RP105-negative B cells. Oral prednisolone improved the affected lesions and the percentage of RP105-negative B cells decreased (3.2%) after the treatment. Case 2: A 53-year-old man with retroperit...

Blood stasis is a very important pathophysiological concept not only in Kampo but also in traditional Chinese medicine. Blood stasis indicates severe disease. Fuku shin (the abdominal exam) and Zetsu shin (the tongue exam) are the most important approaches of the 4 diagnostic procedures in Kampo. Tenderness of the lower abdominal region ( Sho fuku koh man) and distended sublingual veins have be...

Hereditary primary pigmentary degeneration of the retina occurs in a number of experimental animals, the condition closely resembling retinitis pigmentosa in man (Cogan, 1950). In therat, themodeofinheritanceisasanautosomalrecessivecharacteristic (Bourne et al., 1938), whereas in man the situation is more complicated in that at least seven different forms of inheritance have been recognized. In...

A 67-year-old man sustained an anterior dislocation of his right shoulder following a fall down the stairs. He attended the Casualty Department 4 days after his injury. On examination he had no neurovascular injury. Radiographs confirmed anteroinferior dislocation of the shoulder with a comminuted fracture of the greater tuberosity (Fig. 1). Two attempts at closed reduction, under sedation, fai...

In an adult man the mean femoral anteversion angle measures approximately 15 degrees, for which the reasons have never been fully elucidated. An assortment of simian and quadruped mammalian femora was therefore examined and the anteversion angles measured. A simple static mathematical model was then produced to explain the forces acting on the neck of the femur in the quadruped and in man. Femo...