Dried and wet mouse fibroblast monolayers with labeled collagenous substrate were used to study the effects of lipoteichoic acid (LTA) on cellular prolyl hydroxylase activity. LTA is a scavenger of cations, and Fe2+ is essential for prolyl hydroxylase activity. Surprisingly, addition of LTA to dried monolayers resulted in increased prolyl hydroxylase activity, whereas preincubation of Fe2+ with...

Iron (2+ and 3+) is believed to transfer through the three-fold channels in the ferritin shell during iron deposition and release in animal ferritins. However, the rate of iron transit in and out through these channels has not been reported. The recent synthesis of [Fe(CN)6]3-, Prussian Blue (PB) and desferrioxamine (DES) all trapped within the horse spleen ferritin (HoSF) interior makes these ...

This study presents an analysis of a set iron oxides nanoparticles (NPs) (γ-Fe2O3, α-FeOOH, δ-FeOOH, 5Fe2O3·9H2O, and Fe3O4) as potential candidates for ferroptosis therapy in terms phase state, magnetic characteristics, the release Fe2+/Fe3+ ROS mediators. Due to values saturation magnetization Fe3O4 (31.6 emu/g) γ-Fe2O3 (33.8 emu/g), well surface area these particles (130 123 m2/g), it is pos...

BACKGROUND This study examines the dual role of Escherichia coli in the course of ulcerative colitis (UC). The intestinal microbiota is considered to play an important role in UC pathogenesis, but how E. coli contributes to inflammation in UC is still unknown. On the one hand, we demonstrated that there was a significant increase in the number of E. coli at the sites of inflammation in patients...

Reactions of Fe2(CO)6(μ-pdt) (pdt = SCH2CH2CH2S) with aminodiphosphines Ph2PN(R)PPh2 (R = allyl, (i)Pr, (i)Bu, p-tolyl, H) have been carried out under different conditions. At room temperature in MeCN with added Me3NO·2H2O, dibasal chelate complexes Fe2(CO)4{κ(2)-Ph2PN(R)PPh2}(μ-pdt) are formed, while in refluxing toluene bridge isomers Fe2(CO)4{μ-Ph2PN(R)PPh2}(μ-pdt) are the major products. Se...

available online at http://meteoritics.org AUTHOR’S PROOF 981 © The Meteoritical Society, 2008. Printed in USA. Yellow impact glass from the K/T boundary at Beloc (Haiti): XANES determination of the Fe oxidation state and implications for formation conditions Gabriele GIULI1*, Sigrid Griet EECKHOUT2, Christian KOEBERL3, Giovanni PRATESI4, 5, and Eleonora PARIS1 1Dipartimento di Scienze della Te...

Thermoplastic linear ionomer based on sulphonated poly(etherurethane)—styrene-acrylate copolymer, doped with natural Fe2+, was studied by Mössbauer spectroscopy at T = 78 and 290 K to monitor the chemical state of Fe species. The Fe2+ added to aqueous suspension of the system was only partly oxidised in the course of polymer film preparation and drying in air. The oxidised part comprised a magn...

Previous research showed that the heme-requiring human pathogen Haemophilus influenzae lacks the first six of the seven enzymes required for heme synthesis, starting with the precursor, 5-amino levulinic acid. In this study, I demonstrated either directly or by reasonable inference that all 57 strains of H. influenzae examined, including 2 unable to grow on protoporphyrin IX, possess ferrochela...

Mixed Mg-Mn ferrites of compositions Mg0.9 Mn0.1 Inx Fe2-x O4 and Mg0.9 Mn0.1 Aly Fe2-y O4 have been synthesized by the citrate precursor technique. The X-ray diffraction patterns of the samples confirmed the formation of single-phase spinel structure. The ferrites have been investigated for their electric and dielectric properties. The dc resistivity and Curie temperature were found to be incr...

Two commonly used hydrophobic and hydrophilic spin traps for NO, namely Fe2+(DETC)(2)and Fe2+(MGD)(2), respectively, were analyzed via EPR spectroscopy. EPR spectra of trapped NO, together with field position standards, were recorded both in the frozen state and at room temperature. We present a detailed characterization of the EPR spectra of the above paramagnetic NO complexes, concerning g-va...