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PurposeDonor-derived cell-free DNA (dd-cfDNA) has emerged as a reliable, noninvasive method for the detection of allograft rejection in heart transplantation (HT) patients. dd-cfDNA is widely used HT, but its utility multiorgan transplants (HT + another organ) unknown. We describe experience using transplant patients.MethodsRetrospective review all HT patients transplanted between 1998-2022 at ...
Lipopolysaccharide, the major constituent of the outer monolayer of the outer membrane of Gram-negative bacteria, is anchored into the membrane through the hydrophobic moiety lipid A, a hexaacylated disaccharide. The zinc-dependent metalloamidase UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) catalyzes the second and committed step in the biosynthesis of lipid A. LpxC shows no homology to ...
Abstract Funding Acknowledgements Type of funding sources: None. Background Plasma levels and N-terminal pro B-type natriuretic peptide (NT- proBNP), a cardiac neurohormone released in response to increased ventricular stress, represent an important predictor clinical outcomes left (LV) dysfunction; Although, its diagnostic prognostic role patients with acute myocarditis is not completely estab...
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