نتایج جستجو برای: 6 and spi

تعداد نتایج: 16965181  

Journal: :The Journal of biological chemistry 2004
Tsuyoshi Miki Nobuhiko Okada Hirofumi Danbara

The formation of disulfide is essential for the folding, activity, and stability of many proteins secreted by Gram-negative bacteria. The disulfide oxidoreductase, DsbA, introduces disulfide bonds into proteins exported from the cytoplasm to periplasm. In pathogenic bacteria, DsbA is required to process virulence determinants for their folding and assembly. In this study, we examined the role o...

Journal: :Blood 2012
Izumi Sasaki Katsuaki Hoshino Takahiro Sugiyama Chihiro Yamazaki Takahiro Yano Akihiko Iizuka Hiroaki Hemmi Takashi Tanaka Masuyoshi Saito Masanaka Sugiyama Yuri Fukuda Tomokazu Ohta Katsuaki Sato Akira Ainai Tadaki Suzuki Hideki Hasegawa Noriko Toyama-Sorimachi Hiroshi Kohara Takashi Nagasawa Tsuneyasu Kaisho

Plasmacytoid dendritic cells (pDCs), originating from hematopoietic progenitor cells in the BM, are a unique dendritic cell subset that can produce large amounts of type I IFNs by signaling through the nucleic acid-sensing TLR7 and TLR9 (TLR7/9). The molecular mechanisms for pDC function and development remain largely unknown. In the present study, we focused on an Ets family transcription fact...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد یزد - دانشکده کشاورزی 1393

چکیده به منظور رفع مسائل زیست محیطی و اقتصادی استفاده از پلاستیک ها در صنعت و همچنین افزایش زمان ماندگاری مواد غذایی به شکل ایمن، تحقیقات گسترده ای بر روی فیلم ها و پوشش های خوراکی زیست تخریب پذیر انجام شده است. در تحقیقات اخیر به جهت بهبود خواص فیزیکو شیمیایی و مکانیکی فیلم های خوراکی، از ترکیب میزان مختلف پروتئین، لیپید و پلی ساکارید ها برای تولید فیلم های خوراکی مرکب استفاده شده است. در ...

2012
Paul Clarke Rory O'Connor Murat Yilmaz

In an assessment of software process improvement (SPI) in 15 software smalland –medium-sized enterprises (software SMEs), we applied the broad spectrum of software specific and system context processes in ISO/IEC 12207 to the task of examining SPI in practice. Using the data collected in the study, we developed a four-tiered pyramidal hierarchy of SPI for software SMEs, with processes in the hi...

2018
Zhibin Sun Jiadong Fan Haoyuan Li Huaidong Jiang

The advent of ultrafast X-ray free-electron lasers (XFELs) opens the tantalizing possibility of the atomic-resolution imaging of reproducible objects such as viruses, nanoparticles, single molecules, clusters, and perhaps biological cells, achieving a resolution for single particle imaging better than a few tens of nanometers. Improving upon this is a significant challenge which has been the fo...

Journal: :Computers in Human Behavior 2016
Jung-Chieh Lee Yih-Chearng Shiue Chung-Yang Chen

Although numerous studies have discussed the importance of the relationship between knowledge management and software process improvement (SPI), a research gap still exists in relation to how the specific role of knowledge sharing influences successful SPI implementation. This study advances our knowledge by developing an innovative model for exploring the impact of knowledge sharing on SPI suc...

2007
Mahmood Niazi David Wilson Didar Zowghi

The Capability Maturity Model Integration (CMMI) is a structured representation of software development processes that can support an organisation’s software process improvement (SPI) strategies. However, CMMI and SPI initiatives generally exhibit low levels of adoption and limited success. One of the major reasons for these shortcomings is that many organisations undertake SPI initiatives with...

Journal: :Carcinogenesis 2000
K Masumura K Matsui M Yamada M Horiguchi K Ishida M Watanabe K Wakabayashi T Nohmi

Mutations induced by one of the typical dietary mutagens/carcinogens, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), were characterized using gpt delta transgenic mice. This transgenic mouse model has two selection methods to efficiently detect different types of mutations, i.e. 6-thioguanine selection for point mutations and Spi(-) selection for deletions. The mice were fed with a die...

Journal: :The journal of medical investigation : JMI 2006
Rie Shimooka Kido Yasuhiro Naoko Chiba Junko Tanaka Kazuhito Rokutan Harumi Furochi Katsuya Hirasaka Takeshi Nikawa Kyoichi Kishi

In hepatic disorders, abnormal plasma amino acid profiles are observed. In this study, we examined whether soy protein isolate (SPI) improved plasma methionine concentration in the model animals. Portacaval shunt (PCS) increased alanine aminotransferase (ALT) activity and methionine concentration in blood of rats fed a 40% casein diet supplemented with 0.6% methionine (casein-M diet). A 40% SPI...

Journal: :Sustainability 2023

The impact of climate change has led to significant changes in hydroclimatic patterns and continuous stress on water resources through frequent wet dry spells. Hence, understanding effectively addressing the escalating patterns, especially context meteorological drought, necessitates precise modeling these phenomena. This study focuses assessing accuracy drought using well-established Standard ...

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