This edition of the Journal starts with the big questions in psychiatry: what is a diagnosis? And how does one justify treatment against the will of the individual? The next version of the World Health Organization’s bible, the ICD–11, is being prepared at the same time as the American Psychiatric Association’s fifth edition of the DSM. The push for harmonising these two different systems is di...

The fixation process is the first stage in manufacture of histopathological preparations which aims to preserve tissue and harden tissue, so that be observed does not change shape or size. BNF solution (Neutral Buffer Formalin) 10% has been used as a routine fixative It gold standard histology laboratories for decades. material this study was because it easier use can long period time. This det...