نتایج جستجو برای: 6 hydroxy 574 trimethoxyflavone

تعداد نتایج: 982462  

Journal: :Acta Crystallographica Section E Structure Reports Online 2012

Journal: :Acta Crystallographica Section E Structure Reports Online 2009

Journal: :Acta Crystallographica Section E Structure Reports Online 2003

Journal: :Acta Crystallographica Section E Structure Reports Online 2011

Journal: :Drug metabolism and disposition: the biological fate of chemicals 1999
W Jacobsen G Kirchner K Hallensleben L Mancinelli M Deters I Hackbarth L Z Benet K F Sewing U Christians

In an in vitro study, the cytochrome P-450 3A (CYP3A)-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-Co A reductase inhibitors lovastatin and pravastatin were compared. Lovastatin was metabolized by human liver microsomes to two major metabolites: 6'beta-hydroxy [Michaelis-Menten constant (Km): 7.8 +/- 2.7 microM] and 6'-exomethylene lovastatin (Km,10.3 +/- 2.6 mic...

2014
Ken-ichi Ishikawa Atsuko Ishikawa Yoshimi Shoji Takashi Imai

MicroRNA (miRNA) is a type of non-coding RNA that regulates the expression of its target genes by interacting with the complementary sequence of the target mRNA molecules. Recent evidence has shown that genotoxic stress induces miRNA expression, but the target genes involved and role in cellular responses remain unclear. We examined the role of miRNA in the cellular response to X-ray irradiatio...

Journal: :Russian Journal of General Chemistry 2022

Abstract Novel hydrazone and 1,2,4-triazole-3-thione derivatives were obtained via the reaction of N 1 , 3 ,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides with acid hydrazides thiosemicarbazide, respectively. Structure products was proved using IR H NMR spectroscopy methods. Some synthesized compounds tested for antimicrobial activity

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