OBJECTIVES The aim of the study was to correlate the Ki-67 and cyclin A labelling index (LI) with clinical characteristics and risk of recurrence of craniopharyngiomas. METHODS 47 consecutive patients were studied, 21 female and 26 male, aged 34.3 (2.8) years. Immunohistochemical analysis was performed on paraffin wax embedded material using monoclonal antibodies directed against the prolifer...

AIMS To investigate the numbers, morphology, and lineage assignment of Ki-67 positive cells in peripheral blood from normal subjects. METHODS Single and double immunoenzymatic staining procedures, immunoperoxidase, and immunoalkaline phosphatase were used with Ki-67, a monoclonal antibody that recognises a nuclear antigen present in proliferating cells, with markers expressed in B and T lymph...

Objective: Gastric cancer is one of the most common malignant tumors. Non-inversional tool could improve the diagnosis and treatment of the cancer. The aim of this study was to evaluate the diagnostic value of diffusion-weighted imaging (DWI) for histological factors and Ki-67 antigen labelling index (LI) in gastric cancer. Methods: Eight-four DWI images of gastric cancer were analyzed retrospe...

PURPOSE The pterygium is characterized by a fibrovascular neoformation from the bulbar conjunctiva into the cornea. The recent discovery that abnormal markers associated with tumor diseases are identified in the pterygium strengthens the theory that the pterygium is a tumor-like disease rather than a degenerative disease. The CD30 molecule has been identified in neoplastic and normal epithelial...

We investigated CD4 1 and CD8 1 T cell turnover in both healthy and HIV-1–infected adults by measuring the nuclear antigen Ki-67 specific for cell proliferation. The mean growth fraction, corresponding to the expression of Ki-67, was 1.1% for CD4 1 T cells and 1.0% in CD8 1 T cells in healthy adults, and 6.5 and 4.3% in HIV-1–infected individuals, respectively. Analysis of CD45RA 1 and CD45RO 1...

Objective: To evaluate epidermal growth factor receptor and Ki-67 immunohistochemical expression in colorectal adenoma carcinoma cases, to relate their with the available clinicopathological data.Methods: The retrospective study was conducted at Faculty of Medicine, Kafrelsheikh University, Egypt, from September 2019 October 2020, comprised formalin-fixed paraffin-embedded specimens related cas...