829 August 2016, Vol. 106, No. 8 Targeting composite treatment of type 2 diabetes in middle-income countries In the article entitled ‘Targeting composite treatment of type 2 diabetes in middle-income countries – walking a tightrope between hyperglycaemia and the dangers of hypoglycaemia’, which appeared in the January 2016 SAMJ (106(1):57-61), J Wing’s qualifications on the title page should ha...

Article history: Received 1 August 2011 Accepted 28 October 2011 Available online 29 October 2011 Recently, the economic lot scheduling problem (ELSP) with common cycle time and shelf life restrictions has attracted the attention of several researchers. In this paper, a comparative study of solutions given by Xu and Sarker (2003) [Computers & Operations Research 30 (6), 925938] with the results...

Sense of place is rich in theory, but quantitative research approaches often fail to reflect this richness. This schism between theory and application not only impedes the development of theory, but also the ultimate utility of the concept for integration into resource management planning. Here, several fundamental points in sense of place theory that can readily be translated into testable hyp...

We give a more general derivation of the particle velocity and acceleration used in the numerical wave model of Grilli et al. (Int. J. Numer. Meth. Fluids 2001; 35:829–867), by expressing these quantities in a local orthogonal co-ordinate system. Computations of solitary waves propagating and breaking over a sloping bottom show that the new formulation gives better results than the former one i...

Soil Sci. Soc. Am. J. 76:829–844 doi:10.2136/sssaj2011.0090 Received 7 Mar. 2011. *Corresponding author ([email protected]). © Soil Science Society of America, 5585 Guilford Rd., Madison WI 53711 USA All rights reserved. No part of this periodical may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any informat...

with break points in introns 11 and 13 resulting in loss of exons 12 and 13 (Figure 2A and B). Further examination of the region showed a 34-bp repeat (differing by only 1 bp) flanking the break points, suggesting homologous recombination as the mechanism for generating this deletion. The predicted result of this deletion would be that exon 11 splices directly to exon 14 and remains in frame, r...

Synthetic peptides patterned on the amino acid sequences found in two exofacial regions of band 3 protein (residues 824-829 of loop 7 and residues 547-553 of loop 3) blocked, in a dose-dependent fashion, the in vitro adherence of Plasmodium falciparum-infected erythrocytes to C32 amelanotic melanoma cells. Intravenous infusion of these synthetic peptides into Aotus and Saimiri monkeys infected ...

Switching is a local transformation that when applied to a combinatorial object gives another object with the same parameters. It is here shown that the cycle switching graph of the 11 084 874 829 isomorphism classes of Steiner triple systems of order 19 as well as the cycle switching graph of the 1 348 410 350 618 155 344 199 680 000 labeled such designs are connected. In addition to giving an...

In this commentary I utilize the general methods of the mathematical theory of heterogeneous populations in order to point out an omission in the analysis of the mathematical model in [Dwyer et al (2000), Am Nat, 156(2):105–120], which led to the conclusion in [Elderd et al (2008) Am Nat, 172(6):829–842] that the original model must be replaced with an alternative one because of the new data. I...