This study evaluated blood pressure and heart rate responses to exercise and nonexercise tasks as indexes of autonomic function in subjects with and without Down syndrome (DS). Twenty-four subjects (12 with and 12 without DS) completed maximal treadmill exercise, isometric handgrip (30% of maximum), and cold pressor tests, with heart rate and blood pressure measurements. Maximal heart rate and ...

Exercise performance in chronic heart failure is severely impaired, due in part to a peripherally mediated limitation. In addition to impaired maximal exercise capacity, the O(2) uptake (VO(2)) response during submaximal exercise may be affected, with a greater reliance on anaerobiosis leading to early fatigue. However, the response of VO(2) kinetics to submaximal exercise in chronic heart fail...

We investigated the atrial (ANP) and brain natriuretic peptides (BNP), catecholamines, heart rate, and blood pressure responses to graded upright maximal cycling exercise of eight matched healthy subjects and cardiac-denervated heart transplant recipients (HTR). Baseline heart rate and diastolic blood pressure, together with ANP (15.2 +/- 3.7 vs. 4.4 +/- 0.8 pmol/l; P < 0.01) and BNP (14.3 +/- ...

An increased "dose" of endurance exercise training is associated with a greater maximal oxygen uptake (Vo2max), a larger left ventricular (LV) mass, and improved heart rate and blood pressure control. However, the effect of lifelong exercise dose on metabolic and hemodynamic response during exercise has not been previously examined. We performed a cross-sectional study on 101 (69 men) seniors (...

background: to establish a balance between work (physical exercise) and human, the aerobic capacity (vo2max) could be used as a measure. assessing heart rate in association to physiological symptoms is the most commonly used tools for the assessment of fatigue during physical exercise. this study aimed to investigate the association between the aerobic capacity and the heart rate of workers fro...

background: the presence of nitric oxide (no) in the cuneiform nucleus (cnf) has been previously shown. in this study, ng-nitro-l-arginine methyl ester (l-name) (an inhibitor of no synthase), l-arginine (l-arg) (a precursor of no), and sodium nitroprusside (snp) (a donor of no) were microinjected into the cnf and cardiovascular responses were investigated. methods: seventy male rats were divide...

The term cardiac amyloidosis refers to the involvement of the heart as a result of amyloid deposition in heart tissue either in the context of a systemic disease or as a localized form. Several proamyloid proteins can produce amyloid deposits in the heart. Each of these amyloidoses has characteristic clinical (cardiac and extracardiac) features, its own course, and a specific diagnosis and trea...

Introduction: Good functional capacity has a high negative predictive value (NPV) in patients with known or suspected coronary artery disease (CAD) similar to a normal gated myocardial perfusion imaging (GMPI). Aim of this study was to evaluate NPV of functional capacity during treadmill exercise in patients with normal GMPI in Pakistani population. Methods: This was a prospective study which i...