Integration host factor (IHF), a nucleoid-associated protein in bacterial cells, is implicated in a number of chromosomal functions including DNA compaction. IHF binds to all duplex DNA with micromolar affinity and at sequence-specific sites with much higher affinity. IHF is known to induce sharp bends in the helical axis of DNA in both modes of binding, but the role of IHF in controlling DNA c...

It is shown that manufacturing tolerances of the fiber parameters bend radius and numerical aperture (NA) significantly influence the fiber bend loss performance and spectral response of a fiber based edge filter. A theoretical model, validated by experimental results, is used to determine the changes in key spectral parameters for an edge filter, resulting from changes within their manufacturi...

We develop a Landau theory for bend flexoelectricity in liquid crystals of bent-core molecules. In the nematic phase of the model, the bend flexoelectric coefficient increases as we reduce the temperature toward the nematic to polar phase transition. At this critical point, there is a second-order transition from high-temperature uniform nematic phase to low-temperature nonuniform polar phase c...

We demonstrate a technique for tapering periodically an all-solid soft glass fiber, consisting of two types of lead silicate glasses, by the use of a focused CO(2) laser beam and investigate the bend sensing applications of the periodically tapered soft glass fiber. Such a soft glass fiber with periodic microtapers could be used to develop promising bend sensors with a sensitivity of -27.75 μW/...

We have developed artificial haircell sensors based on an improved plastic deformation magnetic assembly (PDMA) method. The PDMA method is uniquely capable of realizing three-dimensional microstructures in an efficient, ICcompatible manner. We have improved the design of the PDMA structure to significantly increase the yield by eliminating stress concentration. The robustness of the fabricated ...

The 2-aminopyridine2-pyridone (2AP2PY) dimer is linked by N-H...O=C and N-H...N hydrogen bonds, providing a model for the Watson-Crick hydrogen bond configuration of the adenine.thymine and adenine.uracil nucleobase pairs. Mass-specific infrared spectra of 2AP2PY and its seven N-H deuterated isotopomers have been measured between 2550 and 3650 cm(-1) by IR laser depletion combined with UV two-c...

RNA, which acts as a medium for transmitting genetic information, plays a variety of roles in a cell. As with proteins, elucidation of the three- dimensional (3D) structures of RNAs is important for understanding their various roles. Determination of the atomic structures of crystallized ribosome has enabled the identification of previously unknown RNA structural motifs. The kink-turn (K-turn o...

We present a novel way to draw planar graphs with good angular resolution. We introduce the polar coordinate representation and describe a family of algorithms for constructing it. The main advantage of the polar representation is that it allows independent control over grid size and bend positions. We first describe a standard (Cartesian) representation algorithm, CRA, which we then modify to ...