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exposed structural components of the outer membrane of Gram-negative bacteria. LPSs consist of lipid A, a core region, and an O-antigen region in many bacteria. LPSs play an important role in the pathogenicity of Gram-negative infections. In experimental animals, purified LPSs induce numerous pathophysiological activities that can lead to shock and death, a condition called “Sepsis”. Most of th...
genus and is predominately distributed in the tropical region of Asia, the Pacific Islands, and Australia. Taccalonolides, anthocyanins, diarylheptanoids and diarylheptanoid glucosides, steroidal sapogenins and steroidal glycosides such as C-27 steroidal saponins, C-28 sterol glucosides and withanolide glucosides have been isolated from some Tacca species. Tacca plantaginea (HANCE) is a perenni...
BACKGROUND Plasmodium and soil transmitted helminth infections (STH) are a major public health problem, particularly among children. There are conflicting findings on potential association between these two parasites. This study investigated the Plasmodium and helminth co-infections among children aged 2 months to 9 years living in Bagamoyo district, coastal region of Tanzania. METHODS A comm...
BACKGROUND Phytochemicals and antioxidants from plant sources are of increasing interest to consumers because of their roles in the maintenance of human health. Most of the secondary metabolites of herbs are used in a number of pharmaceutical products. METHODS Secondary metabolites composition and content of five flavonoids and three phenolic acids were evaluated and determined in Pandanus am...
The green synthesis of metallic nanoparticles is an active research area in nanotechnology. In the present study, antioxidant potential, total reducing capacity and silver nanoparticles (Ag NPs) synthetic potential of methanolic leaf extracts of seven plant species were evaluated and compared. Antioxidant capacity, expressed as µmol Trolox equivalents g-1 DW (µmol TE g-1 DW), ranged from 116.0 ...
Magnetic domain-walls (DWs) with a preferred chirality exhibit very efficient current-driven motion. Since structural inversion asymmetry (SIA) is required for their stability, the observation of chiral domain walls in highly symmetric Pt/Co/Pt is intriguing. Here, we tune the layer asymmetry in this system and observe, by current-assisted DW depinning experiments, a small chiral field which se...
Diffusion-weighted MRI images acquired with multiple b-values have the potential to improve diagnostic accuracy by increasing the conspicuity of lesions and inflammatory activity with background suppression. Unfortunately, the inherently low signal-to-noise ratio (SNR) of DW-MRI reduces enthusiasm for using these images for diagnostic purposes. Moreover, lengthy acquisition times limit our abil...
Background: Multiple sclerosis (MS) is a chronic disease that begins most commonly in young adults and is characterized pathologically by multiple areas of central nervous system (CNS) white matter inflammation, demyelination, and glial scarring. The most valuable aid for diagnosis is magnetic resonance imaging (MRI). New type of MRI has been developed on the basis of molecular diffusion which ...
Objective(s): Copper (Cu) is an essential dietary supplement in animal feeds, which plays an important role in maintaining the balance of all living organisms. Copper nanoparticles (nCu) participate in catalysing activities of multiple antioxidant/defensive enzymes and exerts pro-inflammatory and pro-apoptotic effects on systemic organs and tissues. The present study e...
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