Summary: SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA associated with cancer pathogenesis. It contributes to a variety of cellular functions and recent evidence propounds its association with autophagy process. It has been showed that SOX2OT can regulate the expression of different autophagy associated factors in human cells with different mechanisms, however more remains to ...

Background: The most common types of non-melanoma skin cancer are basal cell carcinoma (BCC), and squamous cell carcinoma (SCC). AKIEC -Actinic keratoses (Solar keratoses) and intraepithelial carcinoma (Bowen’s disease)- are common non-invasive precursors of SCC, which may progress to invasive SCC, if left untreated. Due to the importance of early detection in cancer treatment, this study aimed...

We present a numerical study of a one-dimensional version of the Burridge-Knopoff model [16] of N-site chain of spring-blocks with stick-slip dynamics. Our numerical analysis and computer simulations lead to a set of different results corresponding to different boundary conditions. It is shown that we can convert a chaotic behaviour system to a highly ordered and periodic behaviour by making on...

Gerstmann’s syndrome is caused by a left (dominant) inferior parietal lesion, particularly involving the angular gyrus or subjacent white matter of the left hemisphere. We describe case of an 80 year old right handed man admitted to our hospital with history of sudden onset of blurred vision. At first in neurological examination, he had left hemonymus hemianopia and characteristic features of G...

Gynecological lymphoma is one of the rarest tumors of the female organs that need to be kept in mind in a suspected patient due to its different management protocol. Even though the reported cases of ovarian lymphoma are not limited; our knowledge about diagnosis and treatment of primary cervical lymphoma is restricted. There is a rising number of suggested imaging and pathological criteria tha...

During infection, the influenza A virus non-structural protein 1 (NS1) interacts with a diverse range of viral and cellular factors to antagonize host antiviral defences and promote viral replication. Here, I review the structural basis for some of these functions and discuss the emerging view that NS1 cannot simply be regarded as a 'static' protein with a single structure. Rather, the dynamic ...

Specifically, this study aimed to establish the effects on mortality and morbidity of boarding levels (amount of side-wall trailer ventilation) for finishing pigs in mild weather (8.80 ± 0.30 °C, 71.70% ± 1.12% humidity). Pigs from commercial finishing sites were transported in 302 pot-bellied trailers to commercial processing plants. Measures collected at the processing plant were rates of dea...