The Philadelphia (Ph1) chromosome, in which the hybrid bcr-abl gene is formed, is thought to be the initial event in chronic myelogenous leukemia (CML). The position of the breakpoint within the breakpoint cluster region (bcr) on Ph1 chromosome and the splicing pattern determine the species of the fused bcr-abl messenger RNA (mRNA). We tried to detect the two types of fused mRNAs in 57 chronic-...

Plipastatins have been isolated as part of a program designed to find inhibitors of porcine pancreatic phospholipase A2. They were purified from fermentation broth of Bacillus cereus BMG302-fF67 and finally separated into four fractions by reverse phase HPLC. The respective fractions were designated as plipastatins A1, A2, B1 and B2. Plipastatins also inhibited phospholipases C and D.

This study targeted to optimize process factors using response surface methodology and determining their effect on delignification cellulose recovery. Optimization of pretreatment conditions with desirability value 0.828 was done at temperature (A) 150°C, contact time (B) 2 h, liquid-to-solid ratio (LSR) (C) 15 ml/g. The sample soaked in an aqueous ethanol solution (48% ethanol). Chemical compo...

Although the interest in metallurgical accident investigation of blast furnace gas (BFG) leakage has increased to explore engineering failures, more effort is needed address individual and organizational causative factors clear determine weak links for improving safety management prevention achieve green manufacturing. This study aims examine evolution paths BFG by introducing a combined method...

Bu araştırmanın amacı, yabancılara Türkçe öğretimi ders kitaplarında yer alan yazma etkinliklerinde, farklı seviyelerde becerisinin hangi aşamalarına göre etkinliklere verildiğini ve etkinliklerinde süreciyle ilgili uygulamaların neler olduğunu belirlemektir. doğrultuda, Yeni İstanbul Uluslararası Öğrenciler İçin kitaplarının bütün seviyelerindeki (A1-A2, B1-B2 C1) kitaplarda etkinlikleri doküm...

Bacillus circulans WL-12, isolated as a yeast cell wall-lytic bacterium, secretes a variety of polysaccharide-degrading enzymes into culture medium. When chitinases of the bacterium were induced with chitin, six distinct chitinase molecules were detected in the culture supernatant. These chitinases (A1, A2, B1, B2, C, and D) showed the following distinct sizes and isoelectric points: Mr 74,000,...