نتایج جستجو برای: aaa

تعداد نتایج: 5367  

Journal: :American journal of surgery 2003
Peter H Lin Ruth L Bush Mira Milas Thomas T Terramani Thomas F Dodson Changyi Chen Elliot L Chaikof Alan B Lumsden

BACKGROUND This study was performed to determine the impact of an endovascular program (EVP) on open and endovascular abdominal aortic aneurysm (AAA) operations in a residency training institution. METHODS Over an 8-year period ending in September 2001, hospital records of all patients undergoing open or endovascular AAA repair were retrospectively reviewed. Data were analyzed to determine th...

2017
Jing Kong Ya Zhang Shanshan Liu Hongxuan Li Shangming Liu Jingjing Wang Xiaoteng Qin Xiuxin Jiang Jianmin Yang Cheng Zhang Wencheng Zhang

Abdominal aortic aneurysm (AAA) affects more than 5% of the population in developed countries and the pharmacotherapies for AAA are limited. Here, we explored whether melatonin regulates the development of AAA. In smooth muscle cells, melatonin treatment decreases angiotensin II-induced matrix metalloproteinase 2 (MMP2) and MMP9 expression. Human antigen R (HuR) could bind with the adenylateuri...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2013
Paul E Norman John A Curci

Aneurysmal arterial disease is a vascular degenerative condition that is distinct from atherosclerotic and other occlusive arterial diseases. There is regionalization of the predisposition to aneurysm formation within the vascular tree, and the pathological process varies with location. Infrarenal abdominal aortic aneurysm (AAA) is the most common manifestation of aneurysmal disease, and smokin...

2016
Jiaze Li Smriti Murali Krishna Jonathan Golledge

Abdominal aortic aneurysm (AAA) is a vascular condition that causes permanent dilation of the abdominal aorta, which can lead to death due to aortic rupture. The only treatment for AAA is surgical repair, and there is no current drug treatment for AAA. Aortic inflammation, vascular smooth muscle cell apoptosis, angiogenesis, oxidative stress and vascular remodeling are implicated in AAA pathoge...

2014
Lars Maegdefessel Joshua M. Spin Uwe Raaz Suzanne M. Eken Ryuji Toh Junya Azuma Matti Adam Futoshi Nagakami Helen M. Heymann Ekaterina Chernugobova Hong Jin Joy Roy Rebecka Hultgren Kenneth Caidahl Sonja Schrepfer Anders Hamsten Per Eriksson Michael V. McConnell Ronald L. Dalman Philip S. Tsao

Identification and treatment of abdominal aortic aneurysm (AAA) remain among the most prominent challenges in vascular medicine. MicroRNAs (miRNAs) are crucial regulators of cardiovascular pathology and represent intriguing targets to limit AAA expansion. Here we show, by using two established murine models of AAA disease along with human aortic tissue and plasma analysis, that miR-24 is a key ...

2013
Patrick Yerly George Madeleine Walter Riesen Pascal Bovet

The prevalence of abdominal aortic aneurysm (AAA) and its risk factors are well known in Western countries but few data are available from low- and middle- income countries. We are not aware of systematically collected population- based data on AAA in the African region. We evaluated the prevalence of AAA in a population- based cardiovascular survey conducted in the Republic of Seychelles in 20...

Journal: :Adipocyte 2021

Abdominal aortic aneurysm (AAA) involves the degradation of vascular fibres, and dilation rupture abdominal aorta. Hypoperfusion in walls due to stenosis vasa vasorum is reportedly a cause AAA onset induction adventitial ectopic adipocytes. Recent studies have reported that adipocytes are associated with both human hypoperfusion-induced animal models, highlighting pathological importance hypope...

Journal: :Annals of vascular diseases 2011
Yukio Umeda Matsuhisa Imaizumi Yoshio Mori Hiroshi Takiya

We described the first case of limb ischemia induced by acute aortic dissection in the patient with previous abdominal aortic aneurysm (AAA) repair. A 56-year-old male was referred for severe limb ischemia. He underwent AAA repair one month before the referral. Computed tomography (CT) scan revealed Stanford type B aortic dissection extended to the proximal anastomosis site of the AAA repair. T...

2010
Kosmas I Paraskevas Alexandros A Tzovaras Vassilios Stathopoulos Fotini Gentimi Dimitri P Mikhailidis

The main criterion for abdominal aortic aneurysm (AAA) repair is an AAA diameter >/=5.5 cm. However, some AAAs rupture when they are smaller. Size alone may therefore not be a sufficient criterion to determine rupture risk. Fluorodeoxyglucose (FDG) uptake is increased in the presence of inflammation and it was suggested that this may be a better predictor of rupture risk than AAA size. Furtherm...

Journal: :Annals of internal medicine 2014
Michael L LeFevre

DESCRIPTION Update of the 2005 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for abdominal aortic aneurysm (AAA). METHODS The USPSTF commissioned a systematic review that assessed the evidence on the benefits and harms of screening for AAA and strategies for managing small (3.0 to 5.4 cm) screen-detected AAAs. POPULATION These recommendations apply to asymptomatic...

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