Antigens of the ABO blood group system (i.e., A, B, and H antigens) and Rhesus factor were discovered more than one century ago by karl & steiner [1,2] who is considering the father of transfusion medicine, and with this discovery he enabling physicians to transfuse blood without endangering the patient′s life. The ABO antigens are defined by carbohydrate moieties on the extracellular surface o...

Background: Obesity or a new term globesity is a complex chronic disease involving environmental, genetics, physiologic, metabolic, behavioural, and psychological components. Aim: This study was undertaken to find prevalence of the ABO blood types among the obese individuals. Materials and Methods: Longitudinal and clinical studies were performed in a random sample of the Advanced Medical and D...

Purpose To investigate the association between ABO blood types and clinicopathological characteristics in patients with prostate cancer (PC). Methods A total of 237 pathologically diagnosed PC patients were enrolled. All patients were classified as low-middle or high-risk group. The correlation of ABO blood types with high-risk PC was determined by univariate and multivariate regression analy...

Hemolytic disease of newborn (HDN) is caused by the emergence of inappropriate antibodies against fetal blood antigens, which includes ABO and Rh blood group incompatibility. This study investigated the association between prenatal blood group antibody titer and HDN to provide a theoretic basis for clinical practice. ABO and Rh blood group of 7894 pregnant women and their husbands were screened...

Association between certain systemic diseases and ABO blood group is a well known fact. The purpose of this study was to determine whether there is any association between periodontal disease and ABO blood groups. A cross sectional study was carried-out on 200 subjects who were randomly selected from individuals referred for periodontal treatment. The study subjects were segregated into healthy...

BACKGROUND Fucosylated glycans, including H-antigen, play critical roles in hematopoietic progenitor cell homing, adhesion, growth, and differentiation. H-active antigens are strongly expressed on CD34+ progenitor cells and committed megakaryocytic progenitors and may mediate adhesion to marrow stromal fibroblasts. We examined the possible influence of donor ABO type on platelet (PLT) engraftme...

BACKGROUND ABO blood type locus has been reported to be an important genetic determinant of venous and arterial thrombosis in genome-wide association studies. We tested the hypothesis that ABO blood type alone and in combination with mutations in factor V Leiden R506Q and prothrombin G20210A is associated with the risk of venous thromboembolism and myocardial infarction in the general populatio...

Recent investigations have revealed a correlation between human serum alkaline phosphatase types, the ABO blood groups, and the secretion of ABH substance in the saliva (Arfors, Beckman, and Lundin, 1963a, b; Shreffler, 1964; Beckman, 1964; Evans, 1965; Bamford, Harris, Luffman, Robson, and Cleghorn, 1965). Arfors et al. (1963a) reported that phosphatase type 2 (Pp 2) was uncommon in people hav...

SUMMARY: BACKGROUND: The gene locus for the ABO blood group system encodes a glycosyltransferase. Alterations in the DNA sequence are associated with the blood groups and the expression levels of antigens on red blood cells. A number of ABO alleles have been described as the molecular basis of weak A or B antigens. PATIENTS AND METHODS: Here, we describe a novel variant B allele in a blood dono...

Blood soluble E-selectin (sE-selectin) levels have been related to various conditions such as type 2 diabetes. We performed a genome-wide association study among women of European ancestry from the Nurses' Health Study, and identified genome-wide significant associations between a cluster of markers at the ABO locus (9q34) and plasma sE-selectin concentration. The strongest association was with...