We have developed a quantitative immunoassay chip targeting point-of-care testing. To implement a lateral flow immunoassay, a glass fiber sheet was chosen as the material for the microfluidic channel in which the negative charge on the fiber surfaces efficiently generates the electroosmotic flow (EOF). The EOF, in turn, allows controllable bound/free separation of antigen/antibody interactions ...

A spectral element algorithm is developed to analyze mixed electroosmotic=pressure driven  ows in complex two-dimensional geometries. The new algorithm exhibits spectral accuracy in resolving thin electric double layers. Mixed electroosmotic=pressure driven  ows are simulated in straight channels. Electrokinetic pumping and the means of producing large pressure gradients in microchannels are ...

The electroosmotic flow (EOF) in a poly(dimethylsiloxane) (PDMS) separation channel can be altered and controlled by adding a carboxylic acid to the prepolymer prior to curing. When the prepolymer is doped with 0.5 wt % undecylenic acid (UDA), the electroosmotic mobility in a modified PDMS channel rises to (7.6 +/- 0.2) x 10(-4) cm(2) V(-1) s(-1) (in HEPES buffer at pH 8.5), which is nearly twi...

The capillary/channel length is an important factor in capillary electrophoresis (CE) systems since it is directly related to the amount of separation attainable. In this work we present methods to increase the effective channel length without the need to modify the physical channel length. Using an electrode located close to the capillary surface it is possible to dynamically modify zeta-poten...

  Iontophoresis is one of the skin permeation enhancement methods involving the transport of drugs through the skin under the effect of electrical current. The effect of molecular charge on the iontophoretic permeation of drugs has not been completely understood yet. Therefore the effect of passive and iontophoretic permeation of L-phenylalanine at pH 3.6 (positive charge) and pH 8 (negative ch...

The idea of a microgrid is created by utilizing more diverse ac or dc distributed generation (DG) sources along with an energy storage system (ESS) and loads. The most efficient and reliable selection of ac and dc microgrids is a hybrid ac/dc microgrid. The hybrid microgrid largely overcomes the shortcomings of standalone ac or dc microgrids. A bidirectional interlinking converter (BIC) is util...

DOI: 10.1002/elps.202000086 The cover picture shows the determination of four alkyl sulfate (AS) surfactants (C14, C12, C10, and C8) by capillary electrophoresis (CE) after preconcentration simultaneous adsorption AS on Al2O3 surface. EOF electroosmotic flow (EOF) at high pH pushes move to contactless conductivity detector (C4D). electropherograms show separation in order C14, C8.

We present experimental investigations of electroosmotic pumping using porous borosilicate glass and various low ion density liquids. The orking liquids were deionized water, deuterium oxide (heavy water), methanol, acetone, acetonitrile and a 1 mM sodium borate buffer as a ontrol. We measured ionic conductivity and, as a useful comparative reference, the zeta potential generated by these liqui...

A simple coating procedure employing a sol-gel process to modify the inner surface of a bare fused-silica capillary with a positively charged quaternary ammonium group is established. Scanning electron microscopic studies reveal that a smooth coating with 1 to approximately 2 microm thickness can be obtained at optimized coating conditions. With 40 mM citrate as a running electrolyte, the plot ...