Two isomeric partially acetylated galactocerebrosides, ß-D-galactopyranosyl (2,3,4-tri-O-acetyl)and ß-Dgalactopyranosyl (2,4,6-tri-O-acetyl)-1’(3’-O-acetyl)ceramide, were prepared from galactocerebroside and sulfatide, respectively. Their galactofuranosylation produced ß-D-galactofuranosyl-6and ß-D-galactofuranosyl-3-ß-Dgalactopyranosyl-1’ceramide, as demonstrated by 1 H and 13 C NMR spectra as...

An acute unilateral vestibular lesion leads to a vestibular tone imbalance with nystagmus, head roll tilt and postural imbalance. These deficits gradually decrease over days to weeks due to central vestibular compensation (VC). This study investigated the effects of i.v. N-acetyl-DL-leucine, N-acetyl-L-leucine and N-acetyl-D-leucine on VC using behavioural testing and serial [18F]-Fluoro-desoxy...

Enzymically inactive acetyl-CoA carboxylase [acetyl-CoA:carbon-dioxide ligase (ADP-forming), EC 6.4.1.2] was found as a component of bovine milk-fat-globule membrane (MFGM). Acetyl-CoA carboxylase was present in MFGM at a higher concentration than in cytosolic or mitochondrial fractions of bovine mammary tissue, which makes it unlikely that its presence was due to simple contamination by these ...

The effect of N-acetyl-L-cysteine on interleukin-1beta-induced nitric oxide synthase expression was studied in rat vascular smooth muscle cells to determine if the reduction/oxidation state would modulate cytokine-induced changes. Interleukin-1beta induced the production of nitrite, a stable metabolite of nitric oxide in a time- and dose-dependent manner. Cytokine-induced nitrite production was...

The activation of pyruvate dehydrogenasea kinase activity by CoA esters has been further characterized. Half-maximal activation of kinase activity was achieved with about 1.0 microM acetyl-CoA after a 20-s preincubation in the presence of NADH. More than 80% of the acetyl-CoA was consumed during this period in acetylating sites in the pyruvate dehydrogenase complex as a result of the transacety...

Efficient antimicrobial hydrogels are fabricated by digital light processing (DLP) printing out of a sustainable resin, which is formulated with methacrylated O -acetyl-galactoglucomannan and lignin nanospheres decorated silver nanoparticles.

The metabolism of acetyltryptophan has been studied by various workers. Baldwin and Berg (1) and Rose (2) have reported that acetyl-ntryptophan will not maintain nitrogen balance in the adult human; however, the acetylated L isomer was equal to an equivalent amount of L-tryptophan in this respect. In contrast with these results, Albanese et al. (3) report that, with the exception of a 5 per cen...