In 1957 Landau and Kleffner described an unusual childhood disorder which they termed ‘syndrome of acquired aphasia with convulsive disorder’, in which language regresses after a period of normal development and seizures develop. Children with this disorder typically have severe receptive language difficulties and often are at first thought to be deaf. However, pure-tone audiometry shows normal...

Landau-Kleffner Syndrome (LKS) is a rare, childhood neurological disorder characterized by a sudden or gradual development of acquired aphasia. This case study offers a unique opportunity to assess the changes in the auditory processing ability of a 12 year old male with LKS after two distinct auditory training programs, Fast ForWord® and Dichotic Interaural Intensity Difference (DIID) training...

PURPOSE The language changes experienced by a person with aphasia following a stroke often have sudden and longlasting negative impact on friendships. Friendship relationships are core to social engagement, quality of life, and emotional well-being. The aims of this study were to describe everyday communication with friends for older people with and without aphasia and to examine the nature of ...

PURPOSE This study was aimed to evaluate the brain metabolism in patients with subcortical aphasia after intracerebral hemorrhage (ICH) and the relationship between the severity of aphasia and regional brain metabolism, by using statistical mapping analysis of F-18 fluorodeoxyglucose positron emission tomography (F-18 FDG PET) images. MATERIALS AND METHODS Sixteen right-handed Korean speaking...

BACKGROUND AND PURPOSE One in 3 stroke survivors has aphasia (impaired language comprehension and expressive abilities). Conventionally, depression diagnosis uses language-based methods. We aimed to systematically review methods that have been used to diagnose depression and adaptations to these methods intended for people with aphasia. METHODS We systematically reviewed stroke studies (to Ja...

The present study was conducted on 56 patients (34 females, 22 males), presenting with aphasia due to ischemic insult in the domain of the MCA. Patients were divided into 2 groups to study the short and long-term changes of rCBF in various clinical types of aphasia. They were subjected to thorough neurological examination, assessment of aphasia using modified Chesher test and AAT, laboratory te...

Objectives: Wernicke’s aphasia is one of the most prominent focal brain deficits affecting the comprehension abilities of patients while preserving their production abilities. Although a lot of studies in different languages have been conducted to analyze the nature of this deficit, still some controversies exist in this regard. While some research studies attribute this defect to a performance...

BACKGROUND People with aphasia and their family members are at high risk of experiencing post stroke depression. The impact of early interventions on mood and quality of life for people with aphasia is unknown. METHODS/DESIGN This study will determine whether an early intervention for both the person with aphasia after stroke and their family members leads to better mood and quality of life o...

Topographical evaluation of aphasic brain lesions can enhance our knowledge of cognitive physiology and plasticity. This prospective study was conducted on 100 stroke-afflicted patients with aphasia admitted in Valie-Asr Hospital (Khorasan, Iran) in 2003. Topography of infarct lesions was detected by a neurologist based on the map of brain vascular territories in CT-scan. Aphasic lesions catego...

Despite being perhaps the most studied form of aphasia, the critical lesion location for Broca's aphasia has long been debated, and in chronic patients, cortical damage often extends far beyond Broca's area. In a group of 70 patients, we examined brain damage associated with Broca's aphasia using voxel-wise lesion-symptom mapping (VLSM). We found that damage to the posterior portion of Broca's ...