The general transcription factor IID (TFIID) is required for initiation of RNA polymerase II-dependent transcription at many eukaryotic promoters. TFIID comprises the TATA-binding protein (TBP) and several conserved TBP-associated factors (TAFs). Recognition of the core promoter by TFIID assists assembly of the preinitiation complex. Using cryo-electron microscopy in combination with methods fo...

in this paper we investigate a new notion of bases in hilbert spaces and similarto fusion frame theory we introduce fusion bases theory in hilbert spaces. we also introducea new denition of fusion dual sequence associated with a fusion basis and show that theoperators of a fusion dual sequence are continuous projections. next we dene the fusionbiorthogonal sequence, bessel fusion basis, hilbe...

SummaryBackground The optimal type of ventilation in operating theatres for joint arthroplasty has been debated decades. Recently, the World Health Organization changed its recommendations based on articles that have since criticized. economic and environmental impact is also currently an important research topic but not well investigated. Aim To compare how large, hi...

Aim: to identify factors associated with the symptom severity of thyrotoxic atrial fibrillation (TAF). Patients and Methods: this retrospective study included 70 patients overt hyperthyroidism TAF. The following parameters were used assess TAF severity: type (AF); functional class (f.c.) heart failure (HF) ejection fraction (EF) coexisting AF; evaluation AF-related symptoms using European Heart...

Objective: The aim of this study was to evaluate the inhibitory effect of E. longifolia extract on five human cytochrome P450 isoforms. Methods: The inhibitory effect of E. longifolia standardized extract (TAF-273) on five human cytochrome P450 isoforms, namely CYP1A2, CYP3A4, CYP2C9, CYP2C19 and CYP2D6, was determined using a luminescence method. The effect of eurycomanone on cytochrome P450 i...

The adenovirus (Ad) genome in virion exists in the form of the Ad core, which is a complex of Ad DNA and viral basic proteins. The Ad core supported only initiation and limited elongation in DNA replication in a cell-free system which was developed for DNA replication of naked Ad DNA. We found that addition of a cytoplasmic fraction from uninfected HeLa cells on the top of the system stimulated...

Chronic hepatitis B virus (HBV) infection remains an important global health problem, and may be difficult to manage in clinical practice. Nucleos(t)ide analogues (NAs) with a high barrier resistance (entecavir [ETV], tenofovir disoproxil fumarate [TDF] alafenamide [TAF]) are the most frequently used HBV treatments because of their long-term effectiveness tolerability. ETV less effective patien...