chlamydia pneumoniae is a common respiratory pathogen which is often found in our paediatric populations. many patients with community-acquired pneumonia caused by c. pneumoniae have symptoms suggestive of sinusitis.the role of c. pneumonia in rhinosinusiits children (meanage =4.3 ±2.5year). this case control study was done in the pediatric and ent clinics of hazrat rasul hospital in tehran (20...

B-cells not only produce immunoglobulins and present antigens to T-cells, but also additional key roles in the immune system. Current knowledge on the role of B-cells in infections caused by intracellular bacteria is fragmentary and contradictory. We therefore analysed the phenotypical and functional properties of B-cells during infection and disease caused by Mycobacterium tuberculosis (Mtb), ...

The xenocin operon of Xenorhabdus nematophila consists of xciA and ximB genes encoding a 64-kDa xenocin and 42-kDa immunity protein to kill competing microbes in the insect larva. The catalytic domain of xenocin has RNase activity and is responsible for its cytotoxicity. Under SOS conditions, xenocin is produced with immunity protein as a complex. Here, we show that xenocin and immunity protein...

Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine is the only licensed vaccine against TB, but its protective effect does not extend to controlling the development of infectious pulmonary disease in adults. The development of a more effective vaccine against TB is ...

garlic and onions as dietary constituents and medicines have been used for many disorders which dates back to the early civilization. it has been shown that different species of allium have immunomodulating effects. in this study, we sought to determine if methanolic and chloroformic extracts of allim fistulosum l. (leek) have any effect on cell-mediated immune response in mice. methanolic and ...

this study explored the effects of gnrh agonist (gnrha) immunity on expression of fshr mrna in pituitary and fshr protein in uteri, and also confirmed its efficacy on uterine development. 42 prepuberty and non cyclic ewes were assigned to 6 experimental groups (eg) during anestrus season. animals in eg-i, eg-ii and eg-iii were subcutaneously injected with 200, 300 and 400 μg alarelin antigens (...

background: cigarette smoking has been linked with the suppression of immune responses and increased susceptibility to numerous infections in humans. tetanus is also a major public health problem in many countries. the aim of the present study was to evaluate the serum levels of anti-tetanus toxin antibodies in c igarette smoking and healthy non-smoking people .   materials and methods: a total...

background: the increasing incidence of pertussis among adolescents and adults in recent years is an alarming factor in transmission of the infection to non-immune infants and children. vaccination of pregnant women, immediately after delivery and before being discharged from the hospital may help to protect mothers and their newborns against the disease. decision making process, regarding mate...

background: our information regarding immunity to toxoplasmosis among reproductive age women is indeterminate and there is significant variation between reported results; it is necessary to perform a meta-analysis study on subjects to obtain required findings and develop preventive measures accordingly. objective: estimation level of immunity to toxoplasmosis in reproductive ages. materials and...

conclusions more than 95% of 15 to 25 year-old women (main reproductive age in iran) are within acceptable immunity range. level of immunity to rubella in women of reproductive age in this region appears satisfactory. patients and methods this descriptive cross-sectional study was conducted on 760 women younger than 25 years attending medical centers in ahvaz. a sample of 3 ml of venous blood w...