The widespread use of localization technologies produces increasing quantities of trajectory data. An important task in the analysis of trajectory data is the discovery of moving object clusters, i.e., moving objects that travel together for a period of time. Algorithms for the discovery of moving object clusters operate by applying constraints on the consecutiveness of timestamps. However, exi...

BACKGROUND Yeast pyruvate kinase (PK) catalyzes the final step in glycolysis. The enzyme therefore represents an important control point and is allosterically activated by fructose-1,6-bisphosphate (FBP). In mammals the enzyme is found as four different isozymes with different regulatory properties: two of these isozymes are produced by alternate splicing. The allosteric regulation of PK is dir...

Discovering patterns from data is an important task in data mining. There exist techniques to find large collections of many kinds of patterns from data very efficiently. A collection of patterns can be regarded as a summary of the data. A major difficulty with patterns is that pattern collections summarizing the data well are often very large. In this dissertation we describe methods for summa...

We propose a transactional activity model (TAM) for speciication and management of open-ended cooperative activities. In contrast to each of the extended transaction models which focus more on a formal template for data processing patterns in an application, the activity model contains a set of formal templates, namely activity patterns, for capturing patterns of object interactions in an appli...

Enumeration of pattern-avoiding objects is an active area of study with connections to such disparate regions of mathematics as Schubert varieties and stack-sortable sequences. Recent research in this area has brought attention to colored permutations and colored set partitions. A colored partition of a set S is a partition of S with each element receiving a color from the set [k] = {1, 2, . . ...

We have developed a novel structure-based chemoinformatics approach to search for Complimentary Ligands Based on Receptor Information (CoLiBRI). CoLiBRI is based on the representation of both receptor binding sites and their respective ligands in a space of universal chemical descriptors. The binding site atoms involved in the interaction with ligands are identified by the means of a computatio...

Harvester ants are known as one of the most renowned bio-disturbances in the arid and semi-arid ecosystems that affecte vegetation by collecting seeds and harvesting plants. It seems that physiognomy of plant association in steppe shrub land of Roodshoor, Saveh, Iran has been highly changed by harvester ants’ activities that caused to conduct this research. The study was carried out on active a...

Deoxyribosyl transferases and functionally related purine nucleoside phosphorylases are used extensively for synthesis of non-natural deoxynucleosides as pharmaceuticals or standards for characterizing and quantitating DNA adducts. Hence exploring the conformational tolerance of the active sites of these enzymes is of considerable practical interest. We have determined the crystal structure at ...