Guillain-Barré syndrome (GBS) is an immune-mediated disorder characterized by acute polyneuropathy, ascending paralysis and post infectious polyneuritis. Two-thirds of patients present with a history of recent upper respiratory tract or gastrointestinal infection. The clinical history, neurologic examination and laboratory assessment allow for a straightforward diagnosis in the majority of case...

Myasthenia gravis (Paralysis Suna non Habitualis) is a neuromuscular disease, characterized by fluctuating weakness of skeletal muscles, which is increased by use, at least partially relieved by rest and improves specifically by anticholinesterases. Myasthenic crisis is a life threatening condition in which there is sudden failure in respiratory function due to muscle weakness. It starts with o...

A 54-year-old, right-handed male presented with acute-onset severe headache, vertigo, and vomiting. Initial neurologic examination illustrated dysarthria (lingual), nystagmus (horizontal), left dysmetria on finger-to-nose testing, weakness of the upper lower limb. Magnetic resonance imaging showed lateral medullary infarction (Wallenberg syndrome). The patient was discharged 3 weeks later to an...

A 50-year-old male with a past medical history of borderline hyperlipidemia developed COVID-19 in Fall 2020 and recovered without complication. Approximately 5 months later, he sought care for prolonged episode right-sided weakness that self-resolved. He was diagnosed Transient Ischaemic Attack (TIA) discharged the same day. The following day, persistent hemiplegia an acute left basal ganglia s...

The clinical presentation of acute myocarditis in children may range from asymptomatic to sudden cardiac arrest. This study analyzed the clinical spectrum of acute myocarditis in children to identify factors that could aid primary care physicians to predict the need for extracorporeal membrane oxygenation (ECMO) earlier and consult the pediatric cardiologist promptly. Between October 2011 and S...

Hyperventilation in pregnancy is a cause of chronic respiratory alkalosis. Alkalosis either metabolic or respiratory may cause intracellular shift of potassium ions that may lead to hypokalaemia. However, the resultant hypokalaemia in respiratory alkalosis is usually mild and does not cause much clinical features. A five-months-pregnant female of the age 25 years presented with sudden onset fla...

Guillain-Barré syndrome is clinically characterized by acute onset of generalized, symmetrical, and ascending muscle weakness and areflexia from peripheral nerve involvement. In Guillain-Barré syndrome variants, however, some patients have unusual distribution of muscle involvement. Pharyngeal-cervical-brachial variant of Guillain-Barré syndrome is characterized by oropharyngeal, neck, and uppe...

Dermatomyositis (DM) is an uncommon inflammatory myopathy with characteristic rash accompanying, or more often preceding, muscle weakness. There is a well-recognized association between DM and several cancers, such as ovarian cancer, breast cancer, melanoma, colon cancer, and non-Hodgkin lymphoma. We report the first case of cancer of unknown primary site associated with DM. A 62-yr-old woman p...