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2 Characterization and Modular Composition 3 Noah Davidsohn,†,∥ Jacob Beal,‡,∥ Samira Kiani,† Aaron Adler,‡ Fusun Yaman,‡ Yinqing Li,† Zhen Xie, 4 and Ron Weiss*,† 5 †Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 6 02139, United States 7 ‡Raytheon BBN Technologies, 10 Moulton Street, Cambridge, Massachusetts 02138,...
Pandanothrips gen. n. is described, with three new species inhabiting Pandanus: P. ryukyuensis sp. n. from Japan, P. wangi sp. n. from Malaysia, and P. hallingi sp. n. from Australia. This new genus shows no relationship to Projectothrips Moulton, the only other Thripinae genus known to be associated with Pandanus. Pandanothrips is superficially similar to Danothrips Bhatti, a genus of leaf fee...
Osteoarthritis is a degenerative joint disorder characterized by breakdown of articular cartilage. Degradation of aggrecan, which together with type II collagen provides cartilage with its unique characteristics of compressibility and elasticity, is an early and sustained feature of osteoarthritis. The present work was set up to identify the enzyme(s) responsible for aggrecan breakdown in osteo...
Applying machine learning techniques to the identification of late-onset hypogonadism in elderly men
In the diagnosis of late-onset hypogonadism (LOH), the Androgen Deficiency in the Aging Male (ADAM) questionnaire or Aging Males' Symptoms (AMS) scale can be used to assess related symptoms. Subsequently, blood tests are used to measure serum testosterone levels. However, results obtained using ADAM and AMS have revealed no significant correlations between ADAM and AMS scores and LOH, and the r...
Adam is an experimental language derived from Ada. it was developed to facilitate study of issues in Ada implementation. The two primary objectives which motivated the development of Adam were. to program supervisory packages for multitask scheduling, and to formulate algorithms for compilation of Ada tasking. Adam Is a subset of the sequential program constructs of Ada combined with a set of p...
rd 1998. . An investigation into the application of photo-realistic shadowing techniques for interactive graphics. Resulted in two international conference papers, and one journal paper. Submitted to the University of Bristol, 1998. Dynamic Discontinuity Meshing I have recently completed a PhD in the area of interactive graphics. This entailed the design and implementation of a medium-sized (>1...
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Serotonin transporters (SERTs) have been implicated in various neuropsychiatric disorders. We aim to validate 4-[(18)F]-ADAM (N,N-dimethyl-2-(2-amino-4-[(18)F]fluorophenylthio)benzylamine) as a SERT imaging agent in rats using micro-positron emission tomography (micro-PET) and autoradiography. Sixty to ninety min after injecting 4-[(18)F]-ADAM, specific uptake ratios (SURs) were determined by m...
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